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    Did you mean Protein Kinase C?
    Glossary Protein Kinase C

    enzymes that regulate various cellular functions by phosphorylating proteins

    Protein Kinase C (PKC) is a family of enzymes that play a crucial role in several cellular processes, including cell growth, differentiation, and apoptosis (programmed cell death). These enzymes are activated by signals such as increases in the concentration of calcium ions or diacylglycerol (DAG), and they function by phosphorylating various target proteins, thereby altering their activity. PKC is significant in many physiological and pathological processes, making it a key focus in research related to cancer, cardiovascular diseases, and neurological disorders.

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    1. Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C epsilon transgenic mice by alpha-difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss. PubMed · 2003 · 26 citations
    2. Overexpression of protein kinase C-α in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-α expression but not tumor promotion Journal of Cell Science · 1999 · 135 citations
    3. Protein Kinase C Epsilon Signals Ultraviolet Light-induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism¶ Photochemistry and Photobiology · 2005 · 28 citations
    4. Induction of hair growth by skin irritants and its relation to skin protein kinase C isoforms 1999 · 10 citations
    5. Protein Kinase C Epsilon Signals Ultraviolet Light‐induced Cutaneous Damage and Development of Squamous Cell Carcinoma Possibly Through Induction of Specific Cytokines in a Paracrine Mechanism<sup>¶</sup> Photochemistry and Photobiology · 2005 · 3 citations
    6. Ethanol-induced GABAA receptor alpha4 subunit plasticity involves phosphorylation and neuroactive steroids Molecular and Cellular Neuroscience · 2016 · 11 citations
    7. 측백엽(側柏葉) 추출물의 발모효과(發毛效果)에 관한 실험적 연구 동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine · 2007
    8. Androgen-induced norepinephrine release in male accessory sex organ smooth muscle growth and differentiation 2019
    9. Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic mice. PubMed · 2003 · 79 citations
    10. Cyclosporin A Promotes Hair Epithelial Cell Proliferation and Modulates Protein Kinase C Expression and Translocation in Hair Epithelial Cells Journal of Investigative Dermatology · 2001 · 45 citations
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