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research Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery
A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
research Neuroactive Steroids Inhibit Spinal Reflex Potentiation by Selectively Enhancing Specific Spinal GABAA Receptor Subtypes
Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.
research Sex and Estrous Cycle Influence Diazepam Effects on Anxiety and Memory: Possible Role of Progesterone
Diazepam's effects on anxiety and memory differ between male and female rats due to hormonal influences.
research Phase-Specific Differential Regulation of Mechanical Allodynia in a Murine Model of Neuropathic Pain by Progesterone
Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.
research Progesterone Promotes the Survival of Newborn Neurons in the Dentate Gyrus of Adult Male Mice
Progesterone helps adult male mice's brain cells survive and improves learning and memory.
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5 / 176 resultscommunity Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?
The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.
community Kintor’s KX-826 Pyrilutamide!!
KX-826 hair loss treatment completed trials with mild side effects. GT20029 may be ultimate cure, destroying androgen receptors causing baldness.
community Diagnosed with female pattern hair loss as a male with recent aggressive loss. Preemptively mourning the only part of myself I’ve ever come close to loving. Lost all motivation to do anything with my life.
The conclusion of the conversation is that the user should consider using treatments such as finasteride, minoxidil, and RU58841 to potentially reverse their hair loss. Other suggestions include using hair loss concealers and maintaining a healthy diet.
community The Ultimate Guide to growing your hair back (revised).
Hair loss treatments include using finasteride, dutasteride, and RU58841. Lifestyle changes like increasing carb intake and moderate alcohol consumption are suggested to boost estrogen levels.
community Is this broscience? From More Plates, More Dates
The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.