research Greater Placebo Effect in Topical Than in Systemic Therapies for Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Topical hair loss treatments have a stronger placebo effect than systemic ones.
Search
for
Did you mean Placebo Effect?
Research
5 / 1000+ results 
research Greater Placebo Effect in Topical Than in Systemic Therapies for Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Topical treatments for hair loss have a stronger placebo effect than systemic ones.
research Placebo effect of topical and oral treatments for androgenetic alopecia A systematic review and meta-analysis
Placebo treatments can improve hair growth and satisfaction in hair loss.
research Placebo effect of topical and oral treatments for androgenetic alopecia A systematic review and meta-analysis
Placebo treatments can improve hair growth and satisfaction in hair loss.
research The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma (PRP) on Hair Density and Diameter in Androgenetic Alopecia (AGA): A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study.
This study found that intradermal injections of platelet-rich plasma were equally safe and effective for treating androgenetic alopecia, with higher platelet numbers possibly enhancing hair density and follicle diameter.
Community Join
5 / 848 resultscommunity Why hasn’t anybody or any company done experiments on whether minoxidil and finasteride have effects on human collagen and elastin after a year of use compared to placebo? (In vivo not vitro)
The conversation discusses the lack of in vivo studies on the effects of minoxidil and finasteride on human collagen and elastin after a year of use. It highlights the potential benefits of such research for understanding side effects and improving sales, despite challenges like cost and competition.
community The Placebo Group Has It Worse Than The Standard Prescription 0.5mg Group. -The fear is all in your head.
Dutasteride at 0.5mg may have fewer sexual side effects than expected, with many side effects attributed to psychological factors (nocebo effect). The placebo group experienced more side effects, suggesting fear and anxiety might contribute to perceived side effects.
community Caffeine really a DHT blocker or placebo?
Caffeine is not a proven DHT blocker and does not effectively treat hair loss. Minoxidil, finasteride, and RU58841 are more reliable treatments.
community Am I getting results or is this just a placebo?
The conversation is about a user sharing their 40-day progress using dutasteride, topical Minoxidil, keto shampoo, and dermapen for hair loss, seeking opinions on whether the results are real or a placebo effect. Most responses suggest it's too early to see significant results and recommend continuing the treatment for 6-12 months for noticeable changes.
community Dutasteride and TRT study indicates improvement in aging male symptoms and no difference between placebo group and dutasteride group
Dutasteride is recommended for men on testosterone replacement therapy (TRT) with DHT-sensitive hair, as it does not interfere with TRT's anabolic effects and may improve libido and aging male symptoms. Users report varying experiences with libido when switching from finasteride to dutasteride, with some noticing improvements and others experiencing fluctuations.
Learn
8 / 801 results- What side effects or limitations have been reported with Setipiprant use in hair loss research? In the one published hair-loss trial (DuBois 2021, 169 men, 24 weeks), setipiprant produced no significant hair regrowth over placebo. Treatment-related side effects — mostly mild headaches, stomach upset and fatigue — were reported in about a quarter of the setipiprant group versus just over twelve percent on placebo, and no serious events were attributed to the drug. It is an unapproved, experimental compound with no long-term safety data.
- Dutasteride side effects: what the label and studies actually report The Avodart label reports impotence in 4.7% and decreased libido in 3.0% of men in the first six months (1.7% and 1.4% on placebo), with new reports falling after month six; those figures come from BPH trials in older men, and the hair-loss trials in younger men run only six months. The label and studies also flag a PSA drop of about half, a small rise in high-grade prostate cancer in one trial, an observational link to depression, and sexual effects that the label says may persist after stopping.
- What does finasteride do to the female body? Find out its side effects. Finasteride is not approved for hair loss in women anywhere; the one controlled trial, in 137 postmenopausal women at 1 mg daily, found no benefit over placebo, while smaller uncontrolled studies at higher off-label doses report some improvement. It is contraindicated in pregnancy and crushed or broken tablets must not be handled.
- Melatonin: Does it work the same for men and women? No trial has compared melatonin's effect on hair in men versus women. The only placebo-controlled scalp study enrolled 40 women, and the single reported sex difference — shedding fell in women but not men — comes from one uncontrolled 60-person observation, so any difference is unestablished.
learn Setipiprant
learn Dutasteride
learn Finasteride
learn Melatonin
hormone commonly taken for sleep aid has some topical benefits for hair
learn Procyanidin
bioflavonoid found in plants with antioxidant and hair stimulating properties
learn Follistatin
glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Stem Cell Factor
Clinics
2 / 8 results
Experts
— no results