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block enzymes that break down cyclic nucleotides

Phosphodiesterase Inhibitors (PDE Inhibitors or PDEIs) are a class of drugs that block the action of phosphodiesterase enzymes, which are responsible for breaking down cyclic nucleotides like cAMP and cGMP. By inhibiting these enzymes, PDE inhibitors can increase the levels of these cyclic nucleotides, leading to various therapeutic effects such as vasodilation, anti-inflammatory actions, and improved cardiac function. These drugs are used to treat conditions like erectile dysfunction, pulmonary hypertension, and certain types of heart failure.

Related Terms

• Phosphodiesterase
• Enzyme Inhibitors
• cAMP
• cGMP
• PDE5 inhibitors
• PDE4 inhibitors
• Phosphodiesterase
• Erectile Dysfunction Medications
• Vardenafil
• Apremilast