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Did you mean Neutrophil Extracellular Traps?

Glossary Neutrophil Extracellular Traps

web-like structures released by white blood cells to trap pathogens

Neutrophil Extracellular Traps (NETs) are web-like structures composed of DNA, histones, and antimicrobial proteins that are released by neutrophils, a type of white blood cell, to trap and kill pathogens. This process, known as NETosis, helps the immune system control infections but can also contribute to inflammation and tissue damage if not regulated properly.

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research Neutrophil extracellular traps impair regeneration

4 citations , October 2021 in “Journal of Cellular and Molecular Medicine”

This study observed that mature neutrophils and their extracellular traps inhibit wound-induced hair follicle neogenesis in mice, despite being stimulated by pro-regenerative cues.

research Neutrophil extracellular traps impair regeneration

July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that although mature neutrophils and NETs are stimulated by a pro-regenerative cue, their presence actually hinders wound-induced hair follicle regeneration.

research 461: THE PROFIBROGENIC ROLE OF NEUTROPHIL EXTRACELLULAR TRAPS IN STENOTIC CROHN'S DISEASE: A NEW ANTIFIBROTIC TARGET?

May 2022 in “Gastroenterology”

This study investigated the possible role of neutrophil extracellular traps in contributing to fibrosis in stenotic Crohn's disease.

Identification and Single-Cell Analysis of Prognostic Genes Related to Mitochondrial and Neutrophil Extracellular Traps in Bladder Cancer

research Identification and single-cell analysis of prognostic genes related to mitochondrial and neutrophil extracellular traps in bladder cancer

July 2025 in “Scientific Reports”

In this study, researchers identified six novel prognostic biomarkers for bladder cancer and developed a predictive model that effectively stratifies patients into high-risk and low-risk groups based on immune cell infiltration differences and gene expression.

research Advances in molecular pathogenesis of hidradenitis suppurativa: Dysregulated keratins and ECM signaling

5 citations , February 2022 in “Seminars in cell & developmental biology”

This review discusses the complexities of hidradenitis suppurativa pathogenesis, highlighting issues with Notch signaling, immune dysregulation, and the role of keratinocytes and ECM, but reports no new clinical results.

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