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Did you mean Lymphocytic Cicatricial Alopecia?

Glossary Lymphocytic Cicatricial Alopecia

immune system attacks hair follicles, causing permanent scarring

Lymphocytic Cicatricial Alopecia is a type of hair loss where the immune system mistakenly attacks hair follicles, leading to permanent scarring and hair loss. This condition involves lymphocytes, a type of white blood cell, which infiltrate the hair follicles and cause inflammation, eventually destroying the follicles and replacing them with scar tissue.

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Research

5 / 1000+ results

research Topical gabapentin and its relation to cutaneous innervation in symptomatic lymphocytic primary cicatricial alopecia

April 2024 in “Skin health and disease”

In this pilot study, participants with lymphocytic primary cicatricial alopecia who applied 6% topical gabapentin solution twice daily for 12 weeks experienced significant symptom reduction, though there was no noticeable change in nerve fibre density or neuropeptide expression.

research Prevalence and incidence of primary lymphocytic cicatricial alopecias in the United States from 2019 to 2024

May 2026 in “JAAD International”

This article notes the lack of US prevalence data for primary lymphocytic cicatricial alopecias due to the recent introduction of subtype-specific ICD-10 codes and highlights the importance of early diagnosis for hair preservation.

research A Review of Metabolic Dysregulation in Lymphocytic Cicatricial Alopecia: Exploring the Connections and Therapeutic Implications

1 citations , March 2025 in “Journal of Investigative Dermatology”

Metabolic issues may trigger lymphocytic cicatricial alopecia, and treatments targeting these issues could help.

research Diagnosis and Management of Primary Cicatricial Alopecia: Part I

42 citations , January 2008 in “SKINmed/Skinmed”

This review article discusses the classification, epidemiology, diagnostic approach, and patient management of lymphocytic primary cicatricial alopecias, without reporting new clinical results.

research Primary Cicatricial Alopecias

18 citations , October 2012 in “Dermatologic Clinics”

This article discusses primary cicatricial alopecias, a group of rare inflammatory scalp disorders resulting in permanent hair loss, and reports no new findings.

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Community Join

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community You will lose hair if your prostaglandins aren't in balance

56 upvotes 1 year ago

Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

community can someone help me identify these pls

in Treatment 9 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community Fibrosing alopecia in a pattern distribution

in Research/Science 14 upvotes 2 years ago

A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

community Scarring Alopecia and NSAIDs?

4 upvotes 5 years ago

The user suspects scarring alopecia and is exploring NSAIDs and turmeric/pepper for inflammation-related hair loss, having experienced burning and thinning with finasteride and testosterone reduction. They are seeking feedback while unable to afford a dermatologist.

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Learn

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn GHK-Cu

Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.

learn Centella

Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

learn Baicapil

Struggling with patchy hair loss like alopecia areata? Baicapil might help by reducing inflammation and reactivating growth. There is no published trial of Baicapil in alopecia areata. The anti-inflammatory and hair-density claims come from the ingredient's manufacturer and from laboratory work on its plant extracts, in people with androgenetic-type hair loss rather than autoimmune patchy hair loss.

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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