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    Did you mean Lymphocytic Cicatricial Alopecia?
    GlossaryLymphocytic Cicatricial Alopecia

    immune system attacks hair follicles, causing permanent scarring

    Lymphocytic Cicatricial Alopecia is a type of hair loss where the immune system mistakenly attacks hair follicles, leading to permanent scarring and hair loss. This condition involves lymphocytes, a type of white blood cell, which infiltrate the hair follicles and cause inflammation, eventually destroying the follicles and replacing them with scar tissue.

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 8 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  54 upvotes 1 month ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  413 upvotes 2 weeks ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community Lost density 60% all over scalp in 120 days (4months)

      in Update  10 upvotes 10 months ago
      A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.