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Did you mean Lymphocytic Cicatricial Alopecia?

GlossaryLymphocytic Cicatricial Alopecia

immune system attacks hair follicles, causing permanent scarring

Lymphocytic Cicatricial Alopecia is a type of hair loss where the immune system mistakenly attacks hair follicles, leading to permanent scarring and hair loss. This condition involves lymphocytes, a type of white blood cell, which infiltrate the hair follicles and cause inflammation, eventually destroying the follicles and replacing them with scar tissue.

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research Lymphocytic Mediated Alopecia: Histological Classification by Pattern Analysis

29 citations, March 2001 in “Clinics in Dermatology”

Steven Kossard classified lymphocyte-related hair loss into four patterns, each linked to different types of baldness.

research Topical Gabapentin and Its Relation to Cutaneous Innervation in Symptomatic Lymphocytic Primary Cicatricial Alopecia

April 2024 in “Skin health and disease”

Using a special skin cream with gabapentin helped reduce symptoms of a certain scalp condition but didn't change nerve fibers or skin chemicals.

research An Epidemiological Study of 97 Cases of Primary Cicatricial Alopecia in Iran

12 citations, June 2015 in “Dermatology Reports”

Middle-aged women in Iran are most affected by primary cicatricial alopecia, especially discoid lupus erythematous.

research Frontal Fibrosing Alopecia: A New Autoimmune Entity?

6 citations, January 2019 in “Medical Hypotheses”

Frontal Fibrosing Alopecia might be an autoimmune disease.

research Use of Oral Isotretinoin in the Treatment of Frontal Fibrosing Alopecia: Case Series

September 2021 in “Revista Interdisciplinar em Saúde”

Oral isotretinoína effectively stabilizes frontal fibrosing alopecia.

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Community Join

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 5 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.