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Glossary Lichen Planopilaris

rare inflammatory condition causing scarring and permanent hair loss

Lichen Planopilaris (LPP) is a rare inflammatory condition that affects the hair follicles, leading to scarring and permanent hair loss. It is a form of lichen planus that specifically targets the scalp, causing symptoms such as redness, itching, and scaling. Early diagnosis and treatment are crucial to prevent extensive hair loss.

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Research

5 / 1000+ results

research Lichen Planopilaris is a Common Scarring Alopecia among Iraqi Population

6 citations , January 2013 in “Journal of Cosmetics Dermatological Sciences and Applications”

This study found that lichen planopilaris is a common cause of scalp scarring alopecia in adults and has distinctive clinical features that help differentiate it from other similar conditions.

research Stress: an important cofactor in patients with lichenplanopilaris and frontal fibrosing alopecia

January 2026 in “Advances in Dermatology and Allergology”

In this study, patients with lichen planopilaris and frontal fibrosing alopecia reported a substantial impairment in quality of life and experienced high levels of stress, often considering stress a cause of their condition.

research Pruritus in Lichen Planopilaris and Frontal Fibrosing Alopecia—Clinical Characteristics and Dermoscopic Correlations

August 2024 in “Journal of Clinical Medicine”

This study aimed to assess pruritus in lichen planopilaris and frontal fibrosing alopecia, analyzing its correlation with dermoscopic features, but it reports no specific clinical results.

research Postmenopausal frontal fibrosing alopecia: A frontal variant of lichen planopilaris

329 citations , January 1997 in “Journal of the American Academy of Dermatology”

This study reports that progressive frontal fibrosing alopecia, a distinct and gradually stabilizing form of lichen planopilaris affecting elderly women and often involving eyebrow hair loss, lacks effective treatments.

research Cutaneous and Mucosal Lichen Planus: A Comprehensive Review of Clinical Subtypes, Risk Factors, Diagnosis, and Prognosis

291 citations , January 2014 in “The Scientific World Journal”

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

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Community Join

5 / 44 results

community The Worst Hair Loss Condition You (MAY) have: LPP

48 upvotes 2 years ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Losing Hair on Dutasteride? You might have LPP

96 upvotes 1 year ago

Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

community You will lose hair if your prostaglandins aren't in balance

56 upvotes 1 year ago

Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

community Duta 2,5mg/day - No Progress - 28M

in Update 5 upvotes 1 year ago

A 28-year-old is experiencing hair loss despite using treatments like oral minoxidil, finasteride, and high-dose dutasteride (2.5 mg). They suspect lichen planus might be contributing to the issue and plan to continue treatment while monitoring progress.

community 1mg of finasteride/2 sessions of Kenalog injections/ Clobetasol (4 months into treatment)

5 upvotes 2 months ago

The user is undergoing treatment for hair loss using finasteride, Kenalog injections, and Clobetasol, along with vitamin D and collagen supplements. They are considering additional treatments like minoxidil and microneedling, and there is discussion about whether the hair loss is due to stress, alopecia areata, or a scarring condition like lichen planopilaris.

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Learn

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learn Latanoprost

glaucoma medication with hair follicle stimulant effects

learn PP405

Got small bald patches they say are from stress? PP405 sprays could help bring them back to life. PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.

learn procapil

Tried everything and still getting bald patches? Procapil may help calm the immune response Procapil is a cosmetic ingredient complex; laboratory studies of its individual ingredients report anti-inflammatory effects, but no published clinical trial has tested it in alopecia areata or any other immune-related hair loss. Spreading bald patches should be assessed by a dermatologist.

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