Search

for
Search:

Did you mean Keratinocyte Growth Factor?

Glossary Keratinocyte Growth Factor

stimulates skin and hair cell growth and repair

Keratinocyte Growth Factor (KGF), also known as Fibroblast Growth Factor 7 (FGF-7), is a protein that plays a crucial role in the growth and repair of skin and hair. It specifically stimulates the proliferation and differentiation of keratinocytes, which are the primary cells found in the outer layer of the skin and hair follicles. This makes KGF important in wound healing and potentially beneficial in treating conditions like alopecia.

Related Terms

Research

5 / 1000+ results

research Strengthening the Skin with Topical Delivery of Keratinocyte Growth Factor-1 Using a Novel DNA Plasmid

23 citations , January 2014 in “Molecular Therapy”

This study found that topically delivering KGF-1 DNA plasmid increased epithelial thickness and skin strength, suggesting potential benefits for strengthening compromised skin.

Growth Factors IGF-1 and KGF and Adipose-Derived Stem Cells Promote Migration and Viability of Primary Human Keratinocytes in an In Vitro Wound Model

research Growth factors IGF-1 and KGF and adipose-derived stem cells promote migration and viability of primary human keratinocytes in an in vitro wound model

8 citations , February 2025 in “Frontiers in Medicine”

This study suggests that using growth factors and ADSC-conditioned medium can enhance keratinocyte viability and migration in epidermal transplantation, potentially improving chronic wound healing rates with a patient-dependent effect.

research Production of a 135-residue long N-truncated human keratinocyte growth factor 1 in Escherichia coli

5 citations , May 2023 in “Microbial Cell Factories”

This study found that a newly produced version of KGF-1 with 135 residues maintained biological activity and could serve as an alternative to the standard 140-residue KGF-1.

research Production of a 135-residue long N-truncated human keratinocyte growth factor 1 in Escherichia coli

2 citations , May 2022 in “Research Square (Research Square)”

This study demonstrates that the amino-terminally shortened KGF-1 variant with 135 residues maintains biological activity, suggesting it may serve as an alternative to the original KGF-1 for certain therapeutic applications.

Differential Effects of Caffeine on Hair Shaft Elongation, Matrix and Outer Root Sheath Keratinocyte Proliferation, and Transforming Growth Factor-β2/Insulin-Like Growth Factor-1-Mediated Regulation of the Hair Cycle in Male and Female Human Hair Follicles In Vitro

research Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and transforming growth factor‐β2/insulin‐like growth factor‐1‐mediated regulation of the hair cycle in male and female human hair folliclesin vitro

60 citations , May 2014 in “British Journal of Dermatology”

This study found that caffeine enhanced hair growth and keratinocyte proliferation in human hair follicles, with female follicles showing greater sensitivity than male ones.

View more "keratinocyte growth factor-1" in research →

Learn

6 / 9 results

learn Epidermal Growth Factor

learn Stem Cell Factor

What is stem cell factor and why is it used in hair growth treatments? Stem cell factor promotes hair growth by signaling cell survival and division.
How does stem cell factor help activate dormant hair follicles? Stem cell factor activates dormant hair follicles by signaling through the c-Kit receptor.

learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

learn Thymosin Beta 4

learn Melatonin

hormone commonly taken for sleep aid has some topical benefits for hair

learn Platelet-Rich Plasma

What is Platelet-Derived Growth Factor Beta Polypeptide, and how does it help stimulate new hair growth? PDGF-BB is a growth factor that signals to dermal papilla cells and promotes blood-vessel formation; mouse studies report it can push follicles into the growth phase, and human evidence comes only indirectly from PRP trials. No PDGF product is approved for hair restoration and there is no published human trial of PDGF-BB on its own.

View more "keratinocyte growth factor-1" in learn →

Community Join

5 / 31 results

community DHT Isn’t the Only Factor in Hair Loss and That Might Be the Key to a Real Cure

373 upvotes 6 months ago

Hair loss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.

community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

community Painkillers May Block Minoxidil

12 upvotes 1 year ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

76 upvotes 2 years ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )

6 upvotes 1 year ago

The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.

View more "keratinocyte growth factor-1" in community →

Clinics

6 / 17 results

All 17 clinic results →

Experts

— no results

Try a deeper search in experts →