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research Immunolocalization of junctional proteins in human hairs indicates that the membrane complex stabilizes the inner root sheath while desmosomes contact the companion layer through specific keratins

12 citations , January 2013 in “Acta Histochemica”

Junctional proteins stabilize the inner root sheath and connect the companion layer in human hair.

research Mesenchymal Stem Cells With Modification of Junctional Adhesion Molecule A Induce Hair Formation

8 citations , February 2014 in “Stem cells translational medicine”

This study found that human mesenchymal stem cells overexpressing JAM-A improved hair follicle structure and hair formation in mice by reducing abnormalities such as curved and zigzagged follicles.

research Read-Through for Nonsense Mutations in Type XVII Collagen‒Deficient Junctional Epidermolysis Bullosa

5 citations , April 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

This article discusses junctional epidermolysis bullosa caused by COL17 deficiency, noting a lack of experimental therapies and the impact of nonsense mutations, but it reports no new clinical results.

research P‐35  Nonlethal junctional epidermolysis bullosa in a dog

2 citations , August 2004 in “Veterinary Dermatology”

This case study in an 8-month-old mixed-breed dog with symptoms and histopathological findings supports a diagnosis of hereditary junctional epidermolysis bullosa, although specific genetic mutations weren't identified.

research 0873 Modeling junctional epidermolysis bullosa using tissue-engineered skin substitutes

July 2025 in “Journal of Investigative Dermatology”

Tissue-engineered skin substitutes can model junctional epidermolysis bullosa and may help develop gene therapy.

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community Functional hair follicles grown from stem cells: Scientists have created natural-looking hair that grows through the skin using human induced pluripotent stem cells (iPSCs), a major scientific achievement that could revolutionize the hair growth industry.

171 upvotes 7 years ago

Scientists have grown natural-looking hair from stem cells, potentially revolutionizing hair growth treatments. Concerns include cost, DHT resistance, and the need for future procedures.

community Fully Functional Hair Follicles Have Been Grown in The Lab For The First Time

375 upvotes 6 months ago

Scientists have successfully grown functional hair follicles in the lab, marking a significant advancement in hair regeneration research. A user shared their personal experience with hair loss treatments, including Minoxidil and Finasteride, and plans to share a detailed protocol for hair restoration.

community Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches

4 upvotes 11 years ago

Hair follicle regeneration through stem cell rearrangement is discussed, focusing on bioengineered cellular structures rather than traditional hair transplants. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Experiences with HCG, TRT, DHT for DHT-Sensitive Hair Loss and Functionality Issues

in General 247 upvotes 1 year ago

The user experienced side effects from finasteride and found improved mood and performance with DHT, but it worsened hair loss. They are considering options like TRT, HCG, and topical treatments like Saw Palmetto, but struggle with balancing hair preservation and functionality.

community Anyone tried Kre Alkalyn instead of regular creatine for hair loss concerns?

4 upvotes 1 month ago

The conversation discusses concerns about hair loss potentially linked to regular creatine monohydrate use and considers switching to Kre Alkalyn, which some claim doesn't cause the same issues. A user argues that Kre Alkalyn and regular creatine are functionally identical once ingested, implying no difference in hair loss effects.

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