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    Did you mean Hypothalamic-Pituitary-Adrenal Axis?
    Glossary Hypothalamic-Pituitary-Adrenal Axis

    regulates stress response through hormone release from brain and adrenal glands

    The Hypothalamic-Pituitary-Adrenal (HPA) Axis is a complex network involving the hypothalamus, pituitary gland, and adrenal glands, which work together to regulate the body's response to stress. When you encounter stress, the hypothalamus releases corticotropin-releasing hormone (CRH), prompting the pituitary gland to secrete adrenocorticotropic hormone (ACTH), which in turn stimulates the adrenal glands to produce cortisol, a key stress hormone. This system plays a crucial role in maintaining homeostasis and can impact various bodily functions, including immune response and metabolism.

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    1. Hair loss and hypothalamic-pituitary-adrenocortical axis activity in captive rhesus macaques (Macaca mulatta). PubMed · 2014 · 28 citations
    2. Chronic Stress Suppresses the Expression of Cutaneous Hypothalamic–Pituitary–Adrenocortical Axis Elements and Melanogenesis PLoS ONE · 2014 · 40 citations
    3. Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones Neuropsychopharmacology · 2019 · 197 citations
    4. Involvement of the central hypothalamic-pituitary-adrenal axis in hair growth and melanogenesis among different mouse strains PLoS ONE · 2018 · 6 citations
    5. Alopecia areata – hyperactivity of the hypothalamic–pituitary–adrenal axis is a myth? Journal of the European Academy of Dermatology and Venereology · 2017 · 5 citations
    6. ANALÝZA KORTIZOLU VO VLASOCH – BIOMARKER AKTIVÁCIE HPA OSI 2018
    7. Localized alopecia and suppression of hypothalamic-pituitary-adrenal (HPA) axis in dogs following treatment with difluprednate 0.05% ophthalmic emulsion (Durezol®) BMC veterinary research · 2021 · 2 citations
    8. Gonadal Sex Steroids: Production, Action and Interactions in Mammals InTech eBooks · 2012 · 2 citations
    9. IMPACT OF MERCURY ON SEX HORMONES (LITERATURE REVIEW) Bulletin of Osh State University · 2024 · 1 citations
    10. Hair Cortisol: A Biomarker of Chronic Stress in Animals and its Association with Reproduction Animal Reproduction Update · 2023
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