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    Did you mean Hypothalamic-Pituitary-Adrenal Axis?
    Glossary Hypothalamic-Pituitary-Adrenal Axis

    regulates stress response through hormone release from brain and adrenal glands

    The Hypothalamic-Pituitary-Adrenal (HPA) Axis is a complex network involving the hypothalamus, pituitary gland, and adrenal glands, which work together to regulate the body's response to stress. When you encounter stress, the hypothalamus releases corticotropin-releasing hormone (CRH), prompting the pituitary gland to secrete adrenocorticotropic hormone (ACTH), which in turn stimulates the adrenal glands to produce cortisol, a key stress hormone. This system plays a crucial role in maintaining homeostasis and can impact various bodily functions, including immune response and metabolism.

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    1. Qiviut cortisol reflects hypothalamic–pituitary–adrenal axis activity in muskoxen (Ovibos moschatus) General and comparative endocrinology · 2021 · 7 citations
    2. Involvement of neurosteroids in the control of hypothalamic-pituitary-adrenal axis activity in pregnant sheep under basal and stressful conditions Theriogenology · 2021 · 4 citations
    3. Faculty Opinions recommendation of Hair cortisol levels as a retrospective marker of hypothalamic-pituitary axis activity throughout pregnancy: comparison to salivary cortisol. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2011
    4. Hair cortisol: an indicator of HPA activity in relation to environmental perception in New Zealand White rabbit. CINECA IRIS Institutial Research Information System (University of Genoa) · 2012
    5. Hair loss and hypothalamic-pituitary-adrenocortical axis activity in captive rhesus macaques (Macaca mulatta). PubMed · 2014 · 28 citations
    6. Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones Neuropsychopharmacology · 2019 · 197 citations
    7. Extraction and Analysis of Cortisol from Human and Monkey Hair Journal of Visualized Experiments · 2014 · 101 citations
    8. Correlation of cortisol in 1-cm hair segment with salivary cortisol in human: hair cortisol as an endogenous biomarker Clinical Chemistry and Laboratory Medicine (CCLM) · 2011 · 80 citations
    9. Time course of cortisol loss in hair segments under immersion in hot water Clinica Chimica Acta · 2011 · 76 citations
    10. Corticotropin releasing hormone and the skin Frontiers in bioscience · 2006 · 137 citations
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