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      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

      learn Vitamin D

      vitamin you should probably be taking for general health might also help your hair a little

      learn GHK-Cu

      a copper peptide showing promise in both regrowth and reversing gray hair

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn Sulforaphane

      compound from cruciferous vegetables has some mild effects on DHT

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      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  44 upvotes 5 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Painkillers May Block Minoxidil

      in Research/Science  15 upvotes 2 weeks ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 month ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

      in Research/Science  52 upvotes 3 months ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community SAFFLOWER OIL good alternative for Minoxidil?

      in Treatment  1 upvotes 5 years ago
      Safflower oil is suggested as an alternative to minoxidil for hair growth, with benefits including scalp conditioning and hair strength enhancement. Studies indicate it may also reverse scalp dermatitis, alopecia, and prevent premature grayness.