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GlossaryHaCaT keratinocytes

immortalized human skin cells used in research

HaCaT keratinocytes are a type of human skin cell that has been immortalized, meaning they can divide indefinitely in laboratory conditions. These cells are commonly used in scientific research to study skin biology, wound healing, and diseases like psoriasis and skin cancer because they closely mimic the behavior of normal human skin cells.

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research Inhibition of 5α-Reductase Activity in SZ95 Sebocytes and HaCaT Keratinocytes In Vitro

24 citations , February 2007 in “Hormone and metabolic research”

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

research Eupafolin Nanoparticles Protect HaCaT Keratinocytes from Particulate Matter-Induced Inflammation and Oxidative Stress

43 citations , August 2016 in “International Journal of Nanomedicine”

Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.

research HaCaT Cell Proliferation Influenced by Melatonin

28 citations , January 2003 in “Skin pharmacology and physiology”

Melatonin affects skin cell growth differently based on how much and how long it's used.

research Cold Atmospheric Microwave Plasma Stimulates Dermal Papilla Cell Proliferation by Inducing Beta-Catenin Signaling

February 2023 in “Scientific Reports”

Cold Atmospheric Microwave Plasma (CAMP) helps hair cells grow and could potentially treat hair loss.

Clionasterol-Rich Fraction of Caulerpa Racemosa Against Particulate Matter-Induced Skin Damage Via Inhibition of Oxidative Stress and Apoptosis-Related Signaling Pathway

research Clionasterol-Rich Fraction of Caulerpa Racemosa Against Particulate Matter-Induced Skin Damage Via Inhibition of Oxidative Stress and Apoptosis-Related Signaling Pathway

5 citations , September 2022 in “Antioxidants”

A substance from Caulerpa racemosa seaweed may protect against skin damage caused by air pollution by reducing oxidative stress and cell death.

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community Minoxidil is NOT an Anti-androgen. No.

in Research/Science 43 upvotes 3 months ago

Minoxidil is not an anti-androgen; it is a growth stimulator and does not lower DHT like finasteride or dutasteride. Minoxidil can cause side effects like facial swelling and anxiety due to its vasodilator properties.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 year ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 43 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Anti-oxidants that reverse hairloss?

in Research/Science 88 upvotes 5 years ago

Resveratrol and fisetin, found in red wine and strawberries, may promote hair growth by affecting hair follicle cells. Users discuss various treatments, including natural remedies like saw palmetto and topical applications, with mixed opinions on their effectiveness compared to pharmaceuticals like finasteride.

community Wait, so retinol actually helps with hair growth? I heard it was the other way around a while ago and just accepted it..

in Treatment 7 upvotes 6 years ago

Retinol can help with hair growth, contrary to previous beliefs. Treatments discussed include Minoxidil, finasteride, and RU58841.

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