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research Hairless Suppresses Vitamin D Receptor Transactivation in Human Keratinocytes

78 citations , November 2005 in “Endocrinology”

This study found that Hairless (Hr) acts as a corepressor of the vitamin D receptor (VDR) in human keratinocytes, blocking the action of vitamin D on keratinocyte differentiation.

research Characterization of sciellin, a precursor to the cornified envelope of human keratinocytes

64 citations , April 1992 in “Differentiation”

This study identified Sciellin, a new protein precursor to the cornified envelope in keratinocytes, with unique solubility properties hinting at its potential role in envelope assembly.

research 17β-estradiol Inhibits the Production of RANTES in Human Keratinocytes

56 citations , March 2003 in “Journal of Investigative Dermatology”

This study found that 17β-estradiol inhibited RANTES production in human keratinocytes by suppressing nuclear factor κB activity, suggesting a potential mechanism for 17β-estradiol's modulation of psoriasis-related inflammation.

research Morphogenesis of chimeric hair follicles in engineered skin substitutes with human keratinocytes and murine dermal papilla cells

46 citations , August 2012 in “Experimental Dermatology”

In this study, engineered skin substitutes containing murine dermal papilla cells developed hair follicle-like structures when grafted onto mice, suggesting a model for generating chimeric hair.

research Cysteine Prevents the Reduction in Keratin Synthesis Induced by Iron Deficiency in Human Keratinocytes

40 citations , July 2015 in “Journal of Cellular Biochemistry”

This study found that cysteine supplementation significantly increases keratin expression in human keratinocytes, and counteracts the negative impact of iron deficiency on keratin production by enhancing iron availability for cellular processes.

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community Prevention of age-related beard graying in humans by the topical application of Eriodictyon angustifolium extract

5 upvotes 4 years ago

Topical application of Eriodictyon angustifolium extract can prevent and reverse age-related beard graying and darken gray hair by increasing melanin production. Sterubin, a component of the extract, also promotes hair pigmentation and protects cells from DNA damage.

community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

76 upvotes 2 years ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community Minoxidil is NOT an Anti-androgen. No.

in Research/Science 43 upvotes 9 months ago

Minoxidil is not an anti-androgen; it is a growth stimulator and does not lower DHT like finasteride or dutasteride. Minoxidil can cause side effects like facial swelling and anxiety due to its vasodilator properties.

community My derm said they came up with a new serum that is better then fin? What’s y’all’s thoughts

7 months ago

A new serum claims to enhance hair regrowth by amplifying oxygen delivery, improving the effectiveness of treatments like exosomes and peptides. Users are skeptical, questioning its efficacy compared to established treatments like Minoxidil and Finasteride.

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