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research Culture of the human pilosebaceous unit, hair follicle and sebaceous gland

30 citations , April 2018 in “Experimental Dermatology”

This review discusses the historical development and current challenges in in vitro hair follicle culture, highlighting a need for advanced models using cell lines and tissue engineering, and reports no new results.

research Human hair growth ex vivo is correlated with in vivo hair growth: selective categorization of hair follicles for more reliable hair follicle organ culture

27 citations , November 2005 in “Archives of Dermatological Research”

This study found that selecting human hair follicles at a defined anagen stage based on their in vivo growth rate leads to more consistent results in organ culture, with minoxidil significantly enhancing hair growth in these follicles.

research Reorganization of hair follicles in human skin organ culture induced by cultured human follicle-derived cells

56 citations , July 2005 in “Experimental Dermatology”

This study demonstrated that hair follicle-derived cells can induce hair follicle formation in an in vitro skin organ culture system using human retroauricular skin specimens.

research A method for culturing human hair follicle cells

88 citations , January 1981 in “British Journal of Dermatology”

This study describes a new method for culturing human hair follicle cells, achieving 70% successful growth of keratinocyte colonies using a bovine eye lens capsule substrate.

research Growth kinetics of cultured dermal papilla cells and dermal sheath cells from human hair follicles

January 2000 in “Acta Academiae Medicine Militaris Tertiae”

This study observed that epidermal growth factor significantly enhanced the growth of dermal papilla, dermal sheath cells, and fibroblasts in vitro, particularly benefiting dermal sheath cells.

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Community Join

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community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

community Riken develops new method for culturing hair follicles

41 upvotes 8 years ago

A new stem cell method for culturing hair follicles is being developed as an alternative to Minoxidil, finasteride, and RU58841. There are concerns about its cost and accessibility despite plans for commercialization.

community New study: Vitamin D counteracts DHT in mice and in human hair organ culture and hair cells

126 upvotes 1 year ago

Vitamin D may counteract DHT and help with hair growth, as seen in mice and human hair cultures. Some users discuss using Vitamin D, magnesium, and other supplements for hair health, while others humorously note the success in mice.

community Baldness Breakthrough: microRNA Stimulates Hair Growth in Aging Follicles

316 upvotes 3 years ago

miR-205, a tiny RNA, can stimulate hair growth by softening aging hair follicle stem cells in mice. Future tests aim to see if this can work in humans.

community Why did this recent research paper from professor Tsuji lab in Japan largely go unnoticed by this sub? Isn't this discovery huge? (hair cloning)

35 upvotes 4 months ago

A recent discovery in hair cloning identified a previously unknown cell type essential for hair follicle growth, which could potentially make lab-grown hair viable if translated to humans. However, skepticism remains due to past delays and the challenges of replicating results in humans and making the process affordable.

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Learn

9 / 34 results

learn Ecklonia Cava

Can Ecklonia Cava reactivate dormant hair follicles and support new growth? No human study has tested whether Ecklonia cava reactivates hair follicles; the evidence comes from cultured cells, cultured follicles and mice.

learn Centella

Could nightly oil treatments with centella wake up sleeping follicles? There is no human evidence that centella oil wakes up dormant hair follicles; the only hair-related study is in cultured cells. Community users mention centella as a soothing ingredient, not a regrowth treatment.

learn KY19382

Experimental compound that activates hair-growth signals, tested only in animals

How is KY19382 applied—topically or orally—for hair growth treatment? In every published study KY19382 has been applied topically, never taken orally; the work is preclinical (cells, cultured follicles and mice) and no human trial results have been published.

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Caffeine

Stimulant used in hair shampoos and lotions

learn Dexpanthenol

Provitamin B5, a moisturiser in hair and skin products

learn Rapamycin

Immune-suppressing drug, also called sirolimus

learn Exosomes

Can an exosome treatment revive hair follicles that have stopped producing hair? Unproven. No controlled human study shows that exosomes revive dormant follicles, none can revive scarred ones, and no exosome product is FDA-approved.

learn sh-Polypeptide-7

Does sh-Polypeptide-7 stimulate hair follicles or reduce scalp inflammation? sh-Polypeptide-7 is the INCI name for a lab-made form of human growth hormone (somatotropin) — not EGF, which is sh-Oligopeptide-1. Growth hormone and IGF-1 signalling is documented in hair follicle biology, but there is no published human trial of sh-Polypeptide-7 applied to the scalp for hair growth or scalp inflammation.

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