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Glossary Hormonal Effects

changes in body functions due to hormone activity

Hormonal effects refer to the changes in the body that occur due to the action of hormones, which are chemical messengers produced by glands in the endocrine system. These effects can influence various physiological processes, including growth, metabolism, mood, and reproductive functions. For example, fluctuations in hormones like estrogen and testosterone can impact hair growth and contribute to conditions such as alopecia.

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Research

5 / 1000+ results

research Cardiovascular effects of hormone therapy for prostate cancer

18 citations , July 2015 in “Drug Healthcare and Patient Safety”

This review discusses the benefits and cardiovascular risks of androgen deprivation therapy for prostate cancer patients, noting that optimizing cardiovascular risk factors is important when using ADT.

research The effects of epilation and hormones on the activity of rat hair follicles

37 citations , January 1975 in “Journal of Experimental Zoology”

This study found that thyroxine increased hair growth rate in rats, but estradiol decreased it, with both hormones affecting follicular cycles independently without altering ultimate hair length.

research The effect of a single epilation on successive hair eruptions in normal and hormone‐treated rats

20 citations , January 1979 in “Journal of Experimental Zoology”

In this study, epilation in female rats generally accelerated hair eruption, especially in successive cycles, with variations influenced by hormonal treatments and timing within the hair growth cycle.

research Dermatological effects of menopausal hormone therapy: A path to overcoming hormone phobia

May 2026 in “Meditsinskiy sovet = Medical Council”

This review outlines the benefits of menopausal hormone therapy for improving skin properties in peri- and postmenopausal women, emphasizing that interdisciplinary management enhances quality of life but noting the aesthetic improvements are secondary outcomes.

research Effects of natural products on skin inflammation caused by abnormal hormones secreted by the adrenal gland

2 citations , May 2023 in “Frontiers in Pharmacology”

This review article summarizes findings that suggest natural products may help treat skin inflammation related to abnormal hormone secretion by the adrenal gland, as they can inhibit inflammation pathways and promote wound healing.

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Learn

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learn Estradiol

Is applying Estradiol directly to the scalp effective for hormone-related hair thinning? Applying Estradiol directly to the scalp may help with hormone-related hair thinning.

learn Centella

Sensitive to hormones? A centella scalp mask may help ease hidden inflamm Centella asiatica has anti-inflammatory and wound-healing effects in animal and cell studies, but no published research has tested a centella scalp mask on the human scalp, in hormonal contexts or otherwise, and no community reports were found of one being used this way.

learn Clascoterone

Can I use clascoterone if I'm undergoing gender-affirming hormone therapy? No published clinical trial has tested clascoterone in people on gender-affirming hormone therapy, so its safety in that group is unknown. The FDA label reports low systemic exposure and no described effect on blood testosterone, but it also records HPA-axis suppression and raised potassium in a small minority of subjects.

learn HMI-115

Is HMI-115 considered a safe option, or does it have strong side effects? HMI-115 is an experimental injected antibody, not a hormone blocker: the one published trial (in endometriosis) reported an acceptable 12-week tolerability profile with no treatment-related serious adverse events, and no peer-reviewed safety data exists for its use in hair loss.

learn Baicapil

Losing hair from hormonal imbalance? Baicapil might block DHT without messing with your hormones. No published study shows that Baicapil blocks DHT — the only data on the ingredient itself is the manufacturer's own unpublished dossier, and the baicalin research behind the claim is cancer cell-line work in which the effect was explicitly independent of the androgen receptor.

learn Melatonin

hormone commonly taken for sleep aid has some topical benefits for hair

learn Hydrocortisone

a synthetic cortisol used for anti-inflammatory effects

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

learn Sulforaphane

compound from cruciferous vegetables has some mild effects on DHT

learn Caffeine

the stimulant you know and love can be used topically to stimulate hair

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Community Join

5 / 1000+ results

community Dutasteride Hormone Roller Coaster - Testosterone down, then up, then level, then estrogen up

4 upvotes 3 years ago

Dutasteride effectively stops hair loss but can cause side effects like sexual dysfunction, muscle mass changes, and testicle shrinkage. Adjusting the dosage may help manage these side effects, but long-term health effects remain a concern.

community Anyone else get their hormone levels checked on dutasteride?

in Finasteride/Dutasteride 19 upvotes 1 year ago

Dutasteride effectively reduces DHT levels and significantly increases testosterone levels. Users are cautious about adding oral minoxidil due to potential heart issues and are considering dosage adjustments with medical guidance.

community 22m hormone test - 4months fin, test 3 weeks off fin.

6 upvotes 1 year ago

A 22-year-old male has been using finasteride for 4 months without major side effects but is concerned about hormone test results showing low SHBG and high estrogen. He plans to consult a doctor and is considering alternatives like minoxidil or topical finasteride to avoid health issues.

community Feminizing Hormons wet through the roof with Finasterid

29 upvotes 1 month ago

A user experienced increased estrogen levels after 11 months on finasteride, leading to concerns about feminizing effects. They plan to reduce the finasteride dosage and consider using an aromatase inhibitor to manage estrogen levels.

community Hormone Management Advice - Aromatase Inhibitors , SHBG Blockers

in Finasteride/Dutasteride 5 upvotes 1 year ago

The user plans to switch from minoxidil to finasteride or dutasteride for hair loss, while managing hormones with aromatase inhibitors and SHBG blockers. They seek advice on the best options for these treatments, considering past side effects and future therapies.

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Clinics

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