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GlossaryHLA-DR

protein on immune cells presenting antigens to trigger responses

HLA-DR is a part of the human immune system, specifically a protein found on the surface of certain cells that helps the body distinguish between its own cells and foreign invaders. It plays a crucial role in the immune response by presenting pieces of proteins (antigens) to immune cells, which can then trigger an immune reaction. This protein is also involved in autoimmune conditions, where the immune system mistakenly attacks the body's own tissues.

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Psoriasis Patients Demonstrate HLA-Cw*06:02 Allele Dosage-Dependent T Cell Proliferation When Treated With Hair Follicle-Derived Keratin 17 Protein

research Psoriasis Patients Demonstrate HLA-Cw*06:02 Allele Dosage-Dependent T Cell Proliferation When Treated With Hair Follicle-Derived Keratin 17 Protein

27 citations , April 2018 in “Scientific Reports”

Psoriasis patients' immune response to a hair protein depends on their specific gene type.

research Epigallocatechin-3 Gallate Inhibits STAT-1/JAK2/IRF-1/HLA-DR/HLA-B and Reduces CD8 NKG2D Lymphocytes in Alopecia Areata Patients

15 citations , December 2018 in “International journal of environmental research and public health/International journal of environmental research and public health”

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

Human Adipose-Derived Mesenchymal Stromal Cells Exhibit High HLA-DR Levels and Altered Cellular Characteristics Under Xeno-Free and Serum-Free Conditions

research Human Adipose-Derived Mesenchymal Stromal Cells Exhibit High HLA-DR Levels and Altered Cellular Characteristics Under Xeno-Free and Serum-Free Conditions

12 citations , September 2021 in “Stem Cell Reviews and Reports”

StemMACS media is better for growing therapeutic stem cells than PowerStem media.

research Frontal Fibrosing Alopecia and Lichen Planopilaris in HLA-Identical Mother and Daughter

12 citations , January 2015 in “Indian Journal of Dermatology, Venereology and Leprology”

A mother and daughter with similar hair loss conditions and identical HLA types suggest a genetic link between the conditions.

research Changes in Populations of HLA-DR+CD3+ Cells and CD57–CD16+ Cells in Alopecia Areata After Corticosteroid Therapy

5 citations , January 1994 in “Dermatology”

Corticosteroid therapy reduces specific immune cells and promotes hair growth in alopecia areata patients.

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community Dermastamping — do you use hyaluronic acid as lubricant?

in Microneedling 3 upvotes 1 year ago

The conversation discusses using high molecular weight hyaluronic acid after microneedling to form a protective barrier, though it's considered expensive and offers marginal improvement. Users share experiences with different microneedling tools like derma rollers, dermastamps, and Dr. Pen, with some opting not to use any products on the scalp.