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Glossary Hair Pigmentation

natural hair color determined by melanin in hair follicles

Hair pigmentation refers to the natural color of hair, which is determined by the type and amount of melanin produced by melanocytes in the hair follicles. There are two main types of melanin: eumelanin, which gives hair black or brown color, and pheomelanin, which imparts red or yellow hues. The balance and concentration of these pigments result in the wide variety of hair colors seen in humans.

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Research

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research Unraveling Dermatological Manifestations after COVID-19: Insights from Skin Pigmentation and Hair Loss Patterns

February 2025 in “The Open Dermatology Journal”

In this study conducted at Afzalipour Hospital in Iran, researchers found a significant prevalence of alopecia, particularly resembling telogen effluvium, among COVID-19-recovered patients, with hair loss being more common in females and correlating with arterial oxygen saturation levels.

research Grey hair: clinical investigation into changes in hair fibres with loss of pigmentation in a photoprotected population

17 citations , February 2011 in “International Journal of Cosmetic Science”

This study found that individual differences between pigmented and unpigmented hair fibers in Old Order Mennonites suggest grey hair may be perceived as drier and less manageable due to small mechanical and moisture changes.

Gastrointestinal Polyposis with Protein-Losing Enteropathy, Abnormal Skin Pigmentation, and Loss of Hair and Nails (Cronkhite-Canada Syndrome)

research Gastrointestinal polyposis with protein-losing enteropathy, abnormal skin pigmentation and loss of hair and nails (Cronkhite-Canada syndrome)

26 citations , September 1969 in “The American journal of medicine”

This article reviews Cronkhite-Canada syndrome as a distinct condition from Peutz-Jeghers syndrome and familial polyposis, with cases showing gastrointestinal polyposis, skin, hair, nail abnormalities, and hypoproteinemia.

Complication Following Treatment With a Microneedling Technique for Female Pattern Hair Loss: Hair Dye-Induced Tattoo-Like Pigmentation

research Complication following treatment with a microneedling technique for a female pattern hair loss: hair dye-induced tattoo-like pigmentation

March 2026 in “Portuguese Journal of Dermatology and Venereology”

This study observed an unexpected case where a 44-year-old woman developed linear scalp pigmentation, resembling a tattoo, after undergoing a microneedling procedure followed by hair dyeing two days later, emphasizing the need to advise patients on avoiding hair dye application soon after such treatments.

research A pair of transmembrane receptors essential for the retention and pigmentation of hair

11 citations , May 2012 in “Genesis”

This study in mutant mice found that Bmpr2 and Acvr2a are individually redundant, but together essential for normal hair follicle development, with their reduction causing rapid hair cycling and graying.

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Learn

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learn Scalp Micropigmentation

What is Scalp Micropigmentation and how does it help people with visible hair loss? Scalp Micropigmentation creates the illusion of hair follicles on the scalp for visible hair loss.
Will scalp micropigmentation damage my existing hair or follicles? Scalp micropigmentation does not damage existing hair or follicles.
Can I get scalp micropigmentation after a hair transplant? Yes, scalp micropigmentation can enhance hair density after a hair transplant.
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learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Latanoprost

glaucoma medication with hair follicle stimulant effects

learn Rapamycin

mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

learn Overview

learn Stem Cell Factor

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Community Join

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community Korean treatment that literally made me confident to tie my hair up.

in Treatment 30 upvotes 4 months ago

A user shared their positive experience with MoriTint, a Korean scalp micro pigmentation technique that enhances the appearance of hair density without being permanent. They now offer this service in Los Angeles and emphasize its benefits for those with thinning hair, while clarifying it is not suitable for those with significant hair loss or baldness.

community Hair loss is holding me back from enjoying life and I'm wasting away my youth

279 upvotes 5 months ago

A 31-year-old man feels depressed due to hair loss, using topical finasteride and previously tried minoxidil. Others suggest treatments like finasteride, minoxidil, hair transplants, or embracing baldness, highlighting the importance of mental health and self-acceptance.

community [13-Year Hair Loss Journey – Reached Norwood 7, Trying Again in 2025 (Male, 32, Vietnam)]

245 upvotes 11 months ago

A 32-year-old man from Vietnam, at Norwood 7 hair loss, is using Minoxidil, Finasteride, rosemary oil, NMN, and CoQ10 to regrow hair. Despite minor improvements, alternatives like hair systems or accepting baldness are suggested due to advanced hair loss.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

76 upvotes 2 years ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community White hair seemed to be turn black, re-pigmentation

1 upvotes 10 months ago

The user experienced hair repigmentation and attributes improvements in hair and overall health to a carnivore diet, Boron, and Selenium supplementation. They stopped using finasteride after 20 years, noticed increased testosterone and libido, and observed hair regrowth with RU58841.

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Clinics

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Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

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Hairo Fallas