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GlossaryGGN Repeats

specific DNA sequence repeated within certain genes

GGN repeats refer to a specific sequence of nucleotides (guanine-guanine-nucleotide) that are repeated multiple times within a gene. These repeats can influence the function of the gene and are often studied in the context of genetic disorders and variations. For example, variations in the number of GGN repeats in the androgen receptor gene can affect its activity and have been linked to conditions like androgenic alopecia (male pattern baldness).

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research Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia

195 citations , June 2005 in “American Journal of Human Genetics”

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

research The Androgen Receptor Gene Polyglycine Repeat Polymorphism Is Associated With Memory Performance In Healthy Chinese Individuals

9 citations , March 2009 in “Psychoneuroendocrinology”

Certain gene variations are linked to better memory in healthy Chinese women.

research Polymorphism of CAG and GGN Repeats of Androgen Receptor Gene in Women with Polycystic Ovary Syndrome

9 citations , September 2015 in “Reproductive Biomedicine Online”

Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.

research Androgen Receptor Gene CAG and GGN Polymorphisms in Infertile Nigerian Men

26 citations , November 2009 in “Journal of Endocrinological Investigation”

Certain gene variations are not a major cause of male infertility in Nigerian men.

Androgen Receptor Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males with Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia

research Androgen Receptor Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males with Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia

March 2017 in “European Urology Supplements”

Gene differences affect finasteride side effects in men with hair loss.

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community Long term minoxidil as a permanent solution

in Minoxidil 27 upvotes 4 years ago

A user is considering using minoxidil for hair loss and asks for advice on application and long-term effectiveness. Responses suggest minoxidil can be effective but may lose efficiency over time, and combining it with other treatments like finasteride might be more beneficial.