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Glossary Down syndrome

genetic disorder caused by an extra copy of chromosome 21

Down syndrome, also known as Trisomy 21, is a genetic disorder caused by the presence of an extra copy of chromosome 21. This condition leads to developmental delays, characteristic facial features, and often, various health issues such as heart defects and thyroid problems.

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Research

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Janus Kinase Inhibition in Down Syndrome: Two Cases of Therapeutic Benefit for Alopecia Areata

research Janus kinase inhibition in Down syndrome: 2 cases of therapeutic benefit for alopecia areata

32 citations , April 2019 in “JAAD case reports”

This study discusses the immune dysregulation observed in individuals with Down syndrome, highlighting their increased risk for autoimmune skin conditions, but does not yet clarify the molecular mechanisms behind this profile.

research Alopecia areata in Down syndrome: a clinical evaluation

22 citations , May 2005 in “Journal of the European Academy of Dermatology and Venereology”

This article discusses alopecia areata in individuals with Down syndrome and reports no new clinical findings.

research Down Syndrome and Autoimmune Disease

14 citations , June 2024 in “Clinical Reviews in Allergy & Immunology”

This review highlights a higher prevalence of autoimmune disorders such as thyroid disease, celiac disease, alopecia areata, and vitiligo among individuals with Down syndrome compared to the neurotypical population, suggesting intrinsic immune dysregulation linked to chromosome 21.

research Dermatological aspects of the S2k guidelines on Down syndrome in childhood and adolescence

10 citations , October 2018 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft”

This review discusses the skin and systemic conditions associated with Down syndrome and reports no new clinical results, emphasizing the need for awareness of these manifestations in diagnosis.

research Immunological Profile of Patients Presenting Down Syndrome and Alopecia Areata

1 citations , January 2015 in “Advanced techniques in biology & medicine”

This study found that among patients with Down syndrome, those with alopecia areata may have increased antiperoxidase antibodies, possibly linked to hypothyroidism.

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Community Join

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community So it turns out Post Finasteride Syndrome was never real?

in Finasteride/Dutasteride 271 upvotes 2 years ago

Post Finasteride Syndrome (PFS) is debated, with some users reporting severe side effects from finasteride, while others believe these effects are rare or psychosomatic. Treatments discussed include finasteride, minoxidil, and RU58841.

community Going on what I’ve read fixing e2 (estradiol) levels should cure PFS (post finasteride syndrome)?

4 upvotes 4 years ago

Balancing estradiol (e2) levels may alleviate post-finasteride syndrome (PFS) symptoms. Hormone tests, including testosterone and e2, are recommended for those experiencing PFS.

community if Post Finasteride Syndrome is real. Why is it only the negative effects and not positive have log term effect?

in Finasteride/Dutasteride 63 upvotes 5 months ago

Finasteride is used for hair loss, with mixed reports of no side effects and claims of long-term negative effects known as Post Finasteride Syndrome (PFS). The conversation debates the existence and causes of PFS, with differing opinions on whether it is psychological or real.

community Trying to understand finasteride side effects and post finasteride syndrome

70 upvotes 5 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community White Rice Lowers DHT and might cause post finasteride syndrome

in Finasteride/Dutasteride 4 years ago

White rice may lower DHT and potentially cause symptoms similar to post-finasteride syndrome. The user experienced muscle wasting, depression, and other symptoms after consuming large amounts of white rice.

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Learn

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learn Saw Palmetto

Does saw palmetto prevent hair loss or only slow down hair loss that's already started? Saw palmetto may slow down hair loss but does not prevent it.

learn Ecklonia Cava

How does Ecklonia Cava help slow down hair loss in people with androgenetic alopecia? Ecklonia cava may slow hair loss by inhibiting the enzyme that converts testosterone to DHT.

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Clinics

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49
Hair TransplantSMP
Darling DownsBrisbane, QLD · AU

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