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    Glossary APC Down-Regulated 1

    gene involved in hair growth and development

    APC Down-Regulated 1 (APCDD1) is a gene that plays a role in hair growth and development. Mutations in this gene have been linked to hereditary hypotrichosis simplex, a condition characterized by progressive hair loss starting in childhood. This gene is involved in the Wnt signaling pathway, which is crucial for the regulation of hair follicle development and cycling.

    Research 10 of 812

    1. Hypoxia-Derived Mesenchymal Stem Cell Exosomes Downregulate CXCL12 and Upregulate IL-10 Expression in a Murine Model of Androgenic Alopecia Molecular and Cellular Biomedical Sciences · 2026
    2. Novel small molecules downregulate CDK1 expression and inhibit Wnt/β-catenin signaling in cutaneous squamous cell carcinoma by targeting its distinct tumor-specific cellular landscape Experimental & Molecular Medicine · 2025
    3. The role of Pygo2 during intestinal tumor initiation and progression in vivo 2016
    4. In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population Journal of Investigative Dermatology · 1998 · 101 citations
    5. Argan (Argania Spinosa) press cake extract enhances cell proliferation and prevents oxidative stress and inflammation of human dermal papilla cells Journal of dermatological science · 2021 · 14 citations
    6. Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles Clinical, cosmetic and investigational dermatology · 2023 · 1 citations
    7. The inconsistent regulation of HOXC13 on different keratins and the regulation mechanism on HOXC13 in cashmere goat (Capra hircus) BMC Genomics · 2018 · 17 citations
    8. Anti-proliferative effect of terpenes on human prostate cáncer cells: natural sources and their potential role as chemopreventive agents. Revista chilena de nutrición · 2017 · 3 citations
    9. Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia PLOS ONE · 2012 · 22 citations
    10. IL-17a induces age-related olfactory dysfunction by impairing regeneration and promoting respiratory metaplasia in mice Nature Communications · 2025
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