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Glossary Differential Stripping

technique selectively removes specific layers for detailed analysis

Differential Stripping is a technique used in the study of hair and skin to selectively remove specific layers or components. This method allows researchers to analyze the structure and composition of different layers, such as the cuticle, cortex, and medulla in hair, or the epidermis and dermis in skin, to better understand their individual properties and functions.

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Topical Formulations Containing Finasteride: Determination of Finasteride Penetration into Hair Follicles Using the Differential Stripping Technique

research Topical Formulations Containing Finasteride. Part II: Determination of Finasteride Penetration into Hair Follicles using the Differential Stripping Technique

14 citations , June 2014 in “Journal of Pharmaceutical Sciences”

This study validated the differential stripping technique on hairless rat skin and found that the P-08–016 formulation delivered more finasteride to the epidermis and appendages compared to P-10–008.

research DIFFERENTIAL STRIPPING TECHNIQUE TO DETERMINE FINASTERIDE RETENTION IN HAIR FOLLICLES AFTER IN VITRO TOPICAL APPLICATION

January 2013 in “CINECA IRIS Institutial research information system (University of Pisa)”

research Determination of topically applied finasteride penetrated into hair follicles by using the differential stripping technique

1 citations , January 2012 in “CINECA IRIS Institutial research information system (University of Pisa)”

research Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles

162 citations , August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study introduces a novel non-invasive method called "differential stripping" to quantify the penetration of topically applied substances into hair follicles.

research Methods for quantifying intrafollicular drug delivery: a critical appraisal

34 citations , July 2010 in “Expert Opinion on Drug Delivery”

This review highlights the need for methodologies to understand and quantify drug penetration into hair follicles as significant drug pathways, noting this area lacks comprehensive articles and reports no new results.

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community Finasteride and fertility. Personal report.

in Finasteride/Dutasteride 829 upvotes 1 year ago

Finasteride can affect sperm quality, but fertility usually returns after stopping it, as shown by a user who conceived four months after discontinuation. Some users successfully conceive while on finasteride, though some prefer to pause its use to minimize risks.

community Please explain this Minoxidil phenomena

58 upvotes 2 years ago

The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

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