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GlossaryDesmoglein

protein aiding cell adhesion in skin and tissues

Desmoglein is a type of protein found in the skin and other tissues that helps cells stick together, forming strong connections called desmosomes. These proteins are crucial for maintaining the structural integrity of tissues, and their dysfunction can lead to skin disorders and diseases such as pemphigus, where the skin becomes fragile and blisters easily.

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research A Novel In Vivo Active Pemphigus Model Targeting Desmoglein 1 and Desmoglein 3: A Tool Representing All Pemphigus Variants

2 citations, May 2023 in “Biology”

New mouse models of Pemphigus show severe symptoms and need better treatments.

research Stem Cells and Their Niches

1 citations, January 2013 in “Journal of Investigative Dermatology”

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

research Oxidative Stress and Autoimmune Skin Disease

73 citations, January 2013 in “European journal of dermatology/EJD. European journal of dermatology”

Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.

research 25 Years of Epidermal Stem Cell Research

55 citations, March 2012 in “Journal of Investigative Dermatology”

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

research Biochemistry of Epidermal Stem Cells

26 citations, July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects”

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

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