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    GlossaryDermis (dermal layer)

    thick skin layer beneath epidermis with connective tissue and glands

    The dermis is the thick layer of skin beneath the outer epidermis. It contains connective tissue, blood vessels, hair follicles, and glands, playing a crucial role in skin's structural integrity and elasticity. This layer is essential for thermoregulation and sensation, as it houses nerve endings that respond to touch, pain, and temperature.

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      community JXL082 is not PP405 and Everychem followed the wrong lead

      in Research/Science  40 upvotes 3 months ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

      community 8 month journey. 43 years old.

      in Progress Pictures  1146 upvotes 1 week ago
      A 43-year-old shared an 8-month hair regrowth journey using oral minoxidil, dutasteride, topical minoxidil, ketoconazole shampoo, and lifestyle changes. Commenters noted he looked good both with hair and bald.

      community Testosterone in Reference Range Doesn't Cause Hair Loss

      in Research/Science  51 upvotes 1 year ago
      Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

      community Update: 16 months deep - big 3

      in Progress Pictures  407 upvotes 2 years ago
      The user has seen positive results after 16 months of using topical Finasteride/Minoxidil, microneedling weekly, and Tretinoin for hair loss. There are no reported side effects, and the user advises that the effectiveness of microneedling depends on the pressure applied.