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research The imbalance between Type 17 T-cells and regulatory immune cell subsets in psoriasis vulgaris

49 citations , August 2022 in “Frontiers in Immunology”

This paper discusses the evolving understanding of psoriasis pathogenesis with no new clinical findings; the authors highlight the role of T-cell plasticity and regulatory cells, calling for further clinical applications using single-cell technologies.

Decreased CD200R Expression on Monocyte-Derived Macrophages Correlates with Th17/Treg Imbalance and Disease Activity in Rheumatoid Arthritis Patients

research Decreased CD200R expression on monocyte-derived macrophages correlates with Th17/Treg imbalance and disease activity in rheumatoid arthritis patients

31 citations , February 2014 in “Inflammation Research”

This study found that reduced expression of CD200R1 on monocyte-derived macrophages in rheumatoid arthritis patients was significantly associated with higher disease severity and an imbalance in Th17/Treg cells.

research Severe pustular lesions induced by topical immunotherapy with squaric acid dibutylester for alopecia totalis

1 citations , June 2019 in “Journal of Cutaneous Immunology and Allergy”

This report describes two cases where topical squaric acid dibutylester application in alopecia totalis patients led to severe pustular lesions, necessitating systemic prednisolone treatment.

research Overlapping features of atopic dermatitis and alopecia areata: from pathogenesis to treatment

September 2025 in “Frontiers in Immunology”

This review examines the interconnected processes of atopic dermatitis and alopecia areata, highlighting shared immune imbalances, genetic factors, and microbiome influences, while analyzing current and emerging treatments and identifying gaps in understanding these overlapping conditions.

Alopecia Areata: Genetic and Immunological Insights

research Alopecia Areata

1 citations , January 2017 in “Springer eBooks”

This review discusses recent advances in understanding alopecia areata's disease mechanisms and highlights JAK molecules as promising therapeutic targets, but reports no new clinical results; controlled trials are needed.

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community Gut microbiome imbalances linked to scalp inflammation and hair follicle impact

in Technology 243 upvotes 3 months ago

Gut microbiome imbalances can cause scalp inflammation and affect hair follicles, potentially leading to hair loss. Treatments include finasteride, peptides like BPC-157, TB-500, KPV, and lifestyle changes such as diet and exercise.

community Attempting to assist people with gyno sides on finasteride

23 upvotes 2 years ago

Finasteride can cause gynecomastia due to hormonal imbalances. Management includes consulting an endocrinologist and using aromatase inhibitors like anastrozole or supplements like DIM and zinc.

community I had claude create a protocol only using fda approved drugs.

4 upvotes 8 months ago

A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

community My Theory Of Androgenic Alopecia

16 upvotes 9 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

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