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GlossaryHedgehog Pathway Inhibitors

drugs that block cell growth signals to treat cancer

Hedgehog Pathway Inhibitors are drugs that block the Hedgehog signaling pathway, which is crucial for cell growth and differentiation during embryonic development. In adults, abnormal activation of this pathway can lead to cancers such as basal cell carcinoma. By inhibiting this pathway, these drugs can help treat certain types of cancer by preventing the uncontrolled growth of cancer cells.

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community SCUBE3 and GT20029 could be the closet thing to a cure: Hair Follicle Regeneration and Protection Against DHT

in Research/Science 13 upvotes 1 year ago

SCUBE3 and GT20029 are potential treatments for hair loss, with SCUBE3 stimulating hair growth and GT20029 protecting against DHT. A combined approach using SCUBE3, finasteride or dutasteride, and later GT20029 could provide a comprehensive treatment for androgenetic alopecia.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Physio-metabolic method (antiandrogen, minoxidil, leg training and cold)

in Treatments 309 upvotes 5 months ago

The method combines finasteride, minoxidil, intense leg exercises, and cold exposure to treat androgenetic alopecia. It aims to boost metabolism and reduce androgenic effects, enhancing hair growth.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 6 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

community 9 months fin+microneedling/2 years min, looks like there’s a light at the end of the tunnel

in Progress Pictures 100 upvotes 1 year ago

User shared 9-month progress with finasteride and microneedling, and 2-year progress with minoxidil for hair loss. Others asked about microneedling tools, routine, and suggested micro fibers for improvement.

community Maybe oral min was not that good of an idea for someone this naturally hairy

in Satire 413 upvotes 1 year ago

User discusses increased body hair after using oral minoxidil for hair loss treatment. Others share experiences and debate benefits of being hairy versus bald.

community This Is A Minoxidillo. Could It Hold The Key To Solving Hair Loss?

in Satire 377 upvotes 1 year ago

The conversation is about different treatments for hair loss, including minoxidil, finasteride, RU58841, macroneedling, and pyrilutamice.

community Stop expecting results in 2 months!

in Treatment 125 upvotes 6 months ago

People discussing hair loss treatments emphasize the need for patience, as results from using finasteride and minoxidil can take 8-12 months or longer. Some users report early signs of improvement, while others experience continued shedding or slower progress.

community Source for Pyrilutamide has disappeared

in Treatment 21 upvotes 1 year ago

Anageninc stopping the sale of Pyrilutamide due to a cease and desist order from Kintor, with some speculating that it was either a hoax or subpar product.

community All Drugs in Clinical Trials in 2023

in Research/Science 70 upvotes 1 year ago

12 companies having drugs or therapies in clinical trials during 2023, with various molecules and phases of trial; the probability that some may fail; and progress being made in the field.

community The likely cost of HMI-115, when it comes out

in Technology 11 upvotes 1 year ago

A new potential hair loss treatment called HMI-115, and the cost of this treatment which may be expensive due to production costs but could be competitive with other treatments such as hair transplants.

community Verteporfin update - donor hair regeneration human trial

in Research/Science 23 upvotes 2 years ago

A human trial of verteporfin, a potential treatment for hair loss, with some users noting potential improvements in scarring and overall healing compared to control areas.

community 11 months after Hair transplant 3000 grafts front- minoxidil twice daily foam. Fin 1mg daily. Nizoral shampoo.

in Progress Pictures 731 upvotes 1 year ago

/82 sokak no:3, Bornova, İzmir Province This conversation is about a user's progress after hair transplant surgery and the treatments they used to maintain it. They had a transplant of 3000 grafts in April 2022, taking finasteride 1mg daily and minoxidil twice daily foam, as well as using Nizoral shampoo and Hair Growth Shampoo from Watermans once a week. The results have been positive with good hair health improvement.

community Boys, ALWAYS do your due diligence before going the hair transplant route!

in Transplants 641 upvotes 1 year ago

A user's experiences with hair loss treatments, including finasteride and hair transplants, in relation to another person who has been publicly vocal about their own hair loss struggles. People have shared opinions on this other person's treatment choices and the results of their hair transplant.

community Completely defeated after trying so hard with topical finasteride.

in Finasteride/Dutasteride 24 upvotes 1 year ago

A user who has tried multiple treatments for hair loss, including oral and topical finasteride and liposomal finasteride, but experienced severe side effects in each case; the user is considering trying RU58841 or aromatise inhibitors as alternatives.

community Starting pyrilutamide. Currently have a 2 month supply. I will actually log my results here unlike the others

in Treatment 112 upvotes 2 years ago

Transitioning from finasteride to Pyrilutamide as a treatment for hair loss, and the potential risks associated with taking such a drug. People have discussed the need to wait at least 6 months in order to assess results, and are willing to risk their health trying this new medication.

community Verteporfin day 119 update - donor hair regeneration human trial

in Research/Science 146 upvotes 2 years ago

A human trial of verteporfin, a drug that can inhibit wound healing by scarring and promote regeneration of original tissue and hair follicles to provide an unlimited source for hair transplants; people discussed the potential of this drug and how it could be rolled out in mainstream with more doctors getting on board.

community pyrilutamide log from someone who couldnt take fin/min/ru due to sideeffects

in Progress Pictures 101 upvotes 2 years ago

A user (seblt) who has had side effects from finasteride, minoxidil and RU58841 but is now trying pyrilutamide as a last resort, with other users providing advice and support. They have already seen some baby hairs growing after 10-14 days of treatment and will provide updates in 1-2 weeks.

community What 1 year and $6000 can do for your hair

in Treatment 305 upvotes 2 years ago

A hair transplant performed by Dr Bruno Ferreira in Portugal, which has improved the user's appearance and self-confidence. The user also mentioned taking finasteride for 5 years to help with their hair loss.