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GlossarySonidegib

inhibits Hedgehog pathway to treat advanced basal cell carcinoma

Sonidegib, also known as Odomzo, is a medication used to treat advanced basal cell carcinoma, a type of skin cancer. It works by inhibiting the Hedgehog signaling pathway, which is crucial for the growth and survival of cancer cells.

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research A Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma

25 citations , January 2021 in “Journal of drugs in dermatology”

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

research Experience with Sonidegib in Patients with Advanced Basal Cell Carcinoma: Case Reports

9 citations , May 2022 in “Drugs in Context”

Sonidegib effectively treated advanced basal cell carcinoma with mild side effects.

research Trichoscopy and LC-OCT findings in sonidegib-induced alopecia in patients with advanced basal cell carcinoma

September 2024 in “Dermatology Reports”

Sonidegib often causes hair loss, and LC-OCT helps identify early signs.

research A Sonidegib Experience in the Treatment of Basal Cell Carcinoma with Systemic Lupus Erythematosus: A Case Report

November 2025 in “Clinical Cosmetic and Investigational Dermatology”

research Case Report: PTCH1 splice-site mutation and sonidegib treatment in Gorlin-Goltz syndrome: clinical insights from a family case study

February 2026 in “Frontiers in Medicine”

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