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    Glossary Sonidegib

    inhibits Hedgehog pathway to treat advanced basal cell carcinoma

    Sonidegib, also known as Odomzo, is a medication used to treat advanced basal cell carcinoma, a type of skin cancer. It works by inhibiting the Hedgehog signaling pathway, which is crucial for the growth and survival of cancer cells.

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    Research 30 of 42

    1. A Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma Journal of drugs in dermatology · 2021 · 25 citations
    2. Experience with sonidegib in patients with advanced basal cell carcinoma: case reports Drugs in Context · 2022 · 9 citations
    3. Disproportionality analysis comparing safety profiles of sonidegib and vismodegib based on the FAERS database Scientific Reports · 2025 · 1 citations
    4. Case Report: PTCH1 splice-site mutation and sonidegib treatment in Gorlin-Goltz syndrome: clinical insights from a family case study Frontiers in Medicine · 2026
    5. Pathological Insights into the Limitations of Clinical and Dermoscopic Evaluations in Monitoring Sonidegib Treatment Response for Locally Advanced Basal Cell Carcinoma: A Real-World Study Dermatology and Therapy · 2026
    6. A Sonidegib Experience in the Treatment of Basal Cell Carcinoma with Systemic Lupus Erythematosus: A Case Report Clinical Cosmetic and Investigational Dermatology · 2025
    7. Trichoscopy and LC-OCT findings in sonidegib-induced alopecia in patients with advanced basal cell carcinoma Dermatology Reports · 2024
    8. Emerging drugs and combination strategies for basal cell carcinoma Expert opinion on emerging drugs · 2014 · 19 citations
    9. From basal cell carcinoma morphogenesis to the alopecia induced by hedgehog inhibitors: connecting the dots British Journal of Dermatology · 2017 · 17 citations
    10. Management of Cutaneous and Extracutaneous Side Effects of Smoothened Inhibitor Therapy for Advanced Basal Cell Carcinoma Clinical Cancer Research · 2015 · 16 citations
    11. Evaluation of the Tolerability of Hedgehog Pathway Inhibitors in the Treatment of Advanced Basal Cell Carcinoma: A Narrative Review of Treatment Strategies American Journal of Clinical Dermatology · 2024 · 10 citations
    12. Hair loss and Hedgehog inhibitors: a class effect? British Journal of Dermatology · 2014 · 9 citations
    13. Alopecia due to chemotherapeutics, hedgehog inhibitors, targeted antibody therapies and immune checkpoint inhibitors Deleted Journal · 2024
    14. Roles of the Hedgehog Signaling Pathway in Cutaneous Physiology and Oncology International journal of dermatology and venereology · 2019
    15. Computational Screening of Repurposed Drugs Targeting Sars-Cov-2 Main Protease By Molecular Docking Sudan Journal of Medical Sciences · 2022 · 1 citations
    16. Aberrant Activation of the Hedgehog Pathway in Cutaneous Melanoma: Therapeutic Potential of Pharmacological Inhibitors International Journal of Molecular Sciences · 2026
    17. Giant Morpheaform Basal Cell Carcinoma Mimicking Scarring Alopecia: Exception Prone to Neglect Dermatopathology · 2024
    18. Alopecia in Association with Malignancy: A Review American Journal of Clinical Dermatology · 2018 · 26 citations
    19. Adverse events associated with vismodegib: insights from a real-world pharmacovigilance study using the FAERS database Frontiers in Pharmacology · 2025 · 3 citations
    20. Cancer Treatments and Alopecia: A Systematic Review Turkiye Klinikleri Journal of Internal Medicine · 2021 · 2 citations
    21. Dermatologic Adverse Events from Cancer Treatments Springer eBooks · 2018 · 2 citations
    22. Adverse Hair Reactions to New Targeted Therapies for Cancer Actas Dermo-Sifiliográficas · 2019 · 1 citations
    23. Real-world pharmacovigilance insights into drug-induced risk of alopecia Frontiers in Pharmacology · 2025
    24. Characterization and Management of Hedgehog Pathway Inhibitor-Related Adverse Events in Patients With Advanced Basal Cell Carcinoma ˜The œoncologist · 2016 · 127 citations
    25. Distinct transcriptomic landscapes of cutaneous basal cell carcinomas and squamous cell carcinomas Genes & Diseases · 2019 · 31 citations
    26. Targeting of Smoothened for therapeutic gain Trends in Pharmacological Sciences · 2014 · 105 citations
    27. Cutaneous manifestations and considerations in COVID ‐19 pandemic: A systematic review Dermatologic therapy · 2020 · 101 citations
    28. SARS-CoV-2 Non-Structural Proteins and Their Roles in Host Immune Evasion Viruses · 2022 · 52 citations
    29. Toll-like receptor-targeted anti-tumor therapies: Advances and challenges Frontiers in Immunology · 2022 · 44 citations
    30. A systematic summary of survival and death signalling during the life of hair follicle stem cells Stem Cell Research & Therapy · 2021 · 31 citations