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Did you mean Type XVII Collagen?

GlossaryCollagen XVII

protein crucial for skin structure and integrity

Collagen XVII, also known as COL17 or BP180, is a type of protein found in the skin that plays a crucial role in maintaining the structure and integrity of the skin's basement membrane, which separates the outer layer of skin from the underlying layers. It is essential for skin adhesion and wound healing, and its dysfunction can lead to skin blistering diseases such as bullous pemphigoid.

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Research

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research Type XVII Collagen Coordinates Proliferation in the Interfollicular Epidermis

124 citations, July 2017 in “eLife”

Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.

research Targeting the Stem Cell Niche: Role of Collagen XVII in Skin Aging and Wound Repair

9 citations, January 2022 in “Theranostics”

Collagen XVII is important for skin aging and wound healing.

research Glycome Profiling by Lectin Microarray Reveals Dynamic Glycan Alterations During Epidermal Stem Cell Aging

23 citations, July 2020 in “Aging Cell”

Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.

research Thyroid Diseases and Skin Autoimmunity

24 citations, June 2018 in “Reviews in endocrine and metabolic disorders”

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

research Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis

242 citations, February 2016 in “Science”

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

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Community Join

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community Age-linked hair loss caused by disappearing collagen, researchers say

exz 57 upvotes 5 years ago

Age-linked hair loss is linked to disappearing collagen. Treatments discussed include minoxidil, finasteride, RU58841, tretinoin, microneedling, and collagen supplements.

community For those of you who are getting facial skin side effects (aging, dark circles) from minoxidil, try this, it helped me.

BoomerPhilosophee in Minoxidil 11 upvotes 3 years ago

The conversation provides tips to reduce facial skin side effects from Minoxidil, such as changing pillowcases, sleeping on the back, careful application, hydration, and taking breaks. One reply suggests that alcohol in Minoxidil formulations, not Minoxidil itself, may cause skin aging.

community Wimpole Clinic 1850 grafts (23yo) Dr Malkani

Beautiful-Break543 in Progress Pictures 123 upvotes 4 months ago

A user shared their positive experience with a hair transplant at Wimpole Clinic, performed by Dr. Malkani, and discussed using finasteride at a reduced dose due to side effects. They also mentioned avoiding minoxidil due to heart pain and taking supplements like biotin, marine collagen, viviscal, and krill oil.

community So does oral minoxidil age your skin or not

Simple_Bass_5869 in Minoxidil 41 upvotes 10 months ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community 3 month progress on Topical Minoxidil/Finasteride (Hims), oils, and derma-rolling

janjuana11 in Progress Pictures 2 years ago

This user has been using a combination of topical Minoxidil and Finasteride, oils, biotin, vitamins D and K, and derma-rolling for 3 months to help reduce hair loss. They have experienced some progress but are still looking for more recommendations from others.

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