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Did you mean Chemokine (C-X-C motif) ligand 1?

GlossaryCXCL1 (Chemokine (C-X-C motif) ligand 1)

small protein that attracts white blood cells to inflammation

CXCL1, also known as Chemokine (C-X-C motif) ligand 1 or GROα, is a small protein involved in the immune response. It acts as a signaling molecule that attracts white blood cells to sites of inflammation or injury, playing a crucial role in wound healing and immune defense. In the context of hair biology, CXCL1 can influence hair follicle cycling and may be involved in conditions like alopecia, where hair loss occurs.

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research Rapid Skin Repigmentation on Oral Ruxolitinib in a Patient with Coexistent Vitiligo and Alopecia Areata

157 citations, February 2016 in “Journal of the American Academy of Dermatology”

A man with vitiligo and alopecia saw quick skin and hair improvement with ruxolitinib, but skin color gains were lost after stopping treatment.

Analysis of Hidradenitis Suppurativa-Linked Mutations in Four Genes and the Effects of PSEN1-P242LfsX11 on Cytokine and Chemokine Expression in Macrophages

research Analysis of Hidradenitis Suppurativa-Linked Mutations in Four Genes and the Effects of PSEN1-P242LfsX11 on Cytokine and Chemokine Expression in Macrophages

25 citations, December 2018 in “Human Molecular Genetics”

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

research Molecular Mechanisms Responsible for Therapeutic Potential of Mesenchymal Stem Cell-Derived Secretome

271 citations, May 2019 in “Cells”

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

research Brown Adipose Tissue as an Innovative Approach for Polycystic Ovary Syndrome Treatment: A Narrative Review

October 2023 in “Advancement in yoga and physical therapy”

More research is needed before using brown fat to treat polycystic ovary syndrome.

research Dermal Lymphatic Dilation in a Mouse Model of Alopecia Areata

5 citations, April 2016 in “Experimental and molecular pathology”

Mice with alopecia areata had wider lymphatic vessels in their skin.

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community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 4 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.