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Glossary Central Nervous System

brain and spinal cord controlling body's activities and responses

The Central Nervous System (CNS) consists of the brain and spinal cord, serving as the main control center for the body. It processes sensory information, coordinates voluntary and involuntary actions, and is crucial for functions such as thought, emotion, and movement.

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research Folliculotropic mycosis fungoides with central nervous system involvement: Demonstration of tumor clonality in intrafollicular T cells using laser capture microdissection

14 citations , February 2003 in “Journal of the American Academy of Dermatology”

This case report describes the first use of laser capture microdissection to confirm that atypical lymphocytes in a folliculotropic mycosis fungoides case involving the central nervous system were part of the same tumor clone.

research Central nervous system involvement in autoimmune polyglandular syndrome

10 citations , April 2003 in “Clinical neurology and neurosurgery”

This case study reports a 33-year-old man with autoimmune thyroiditis and alopecia universalis experiencing reversible CNS demyelination, possibly due to autoimmune activity against CNS antigens.

research A Possible Role of Keratinocytes of Skin and Mucous Membranes in Prion Propagation and Transmission

5 citations , December 2002 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

This study suggests that keratinocytes in skin and mucous membranes might be involved in prion disease transmission due to their expression of PrPc, potentially serving as an entry point for prions.

research Involvement of the central hypothalamic-pituitary-adrenal axis in hair growth and melanogenesis among different mouse strains

6 citations , October 2018 in “PLoS ONE”

This study found that chronic stress may inhibit hair follicle growth and melanogenesis in mice through modulation of the central HPA axis, with C57BL/6 mice appearing most sensitive to these effects.

research Revisiting Rosacea Through the Skin–Gut–Brain Axis: A Neuroimmune Perspective

February 2026 in “Life”

In this narrative hypothesis-driven overview, the authors propose reframing rosacea as a neuroimmune disorder, highlighting the interconnected role of the skin-gut-brain axis, particularly central nervous system involvement alongside gut microbiota and neurogenic inflammation, to emphasize the need for multidisciplinary therapeutic approaches.

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community After quitting min and fin I asked AI on how fix the mess I am in and it says:

in Technology 1 year ago

Prolonged use of topical minoxidil and finasteride can lead to neuroendocrine and autonomic dysfunction, causing severe sensitivity and side effects. Recovery involves avoiding these treatments, supporting neurosteroid recovery, calming the sympathetic system, and rebuilding scalp health naturally.

community Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective Dysfunction

in Research/Science 36 upvotes 2 months ago

Androsterone may help with sexual and affective dysfunction from finasteride by replacing disrupted neurosteroids without increasing androgenic side effects. Controlled testing is needed to confirm its effectiveness and safety.

community Creatine increases DHT?!?!

8 upvotes 5 years ago

Creatine may increase DHT, potentially affecting hair loss, but opinions vary. Users discuss using finasteride and alternatives like plant protein to manage hair loss.

community Any success with skipping Finasteride and going straight to Dutasteride daily?

7 upvotes 5 days ago

Some users prefer starting with finasteride due to its shorter half-life and lower DHT inhibition, while others advocate for using dutasteride directly for its higher efficacy. Dutasteride is considered more effective but may have different side effects due to its inability to cross the blood-brain barrier.

community What are the Pros and Cons of taking Oral Minoxidil and Finasteride (Pills) Sublingually?

in Treatments 167 upvotes 10 months ago

The user is considering taking 2.5 mg oral minoxidil and 1 mg oral finasteride sublingually to minimize side effects after a hair transplant. They seek advice on the pros and cons of this method, noting a lack of concrete information.

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