Search
for

    Glossary Cell cycle inhibitor

    molecule that halts or slows down cell division

    A cell cycle inhibitor, also known as a cell cycle suppressor or cell cycle regulator, is a molecule that can halt or slow down the process of cell division. These inhibitors play a crucial role in controlling cell growth and ensuring that cells do not divide uncontrollably, which is important for preventing conditions like cancer. For example, proteins like p21 and p27 are well-known cell cycle inhibitors that can stop the cell cycle at specific checkpoints, allowing for DNA repair or triggering cell death if the damage is irreparable.

    Related Terms

    Research 10 of 1000+

    1. Embryonic NIPP1 depletion in keratinocytes triggers a cell-cycle arrest and premature senescence in adult mice Journal of Investigative Dermatology · 2024
    2. 1409 Temporary cell cycle arrest by ALRN-6924: A novel, p53-targeting strategy to protect human scalp hair follicles against cyclophosphamide-induced alopecia Journal of Investigative Dermatology · 2023
    3. Immune cell regulation of the hair cycle Experimental Dermatology · 2020 · 27 citations
    4. New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence Journal of Investigative Dermatology · 2012 · 68 citations
    5. Circ-Smad5 retards the G1/S transition of cell cycle via inhibiting the activity of wnt/lef/cyclind1 signaling in JB6 cells Genes & Diseases · 2020 · 10 citations
    6. Editorial: Stem cell exhaustion in aging Frontiers in Aging · 2024 · 13 citations
    7. Injury suppresses Ras cell competitive advantage through enhanced wild-type cell proliferation bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 1 citations
    8. Data from Synergistic Function of Smad4 and PTEN in Suppressing Forestomach Squamous Cell Carcinoma in the Mouse 2023
    9. Data from Synergistic Function of Smad4 and PTEN in Suppressing Forestomach Squamous Cell Carcinoma in the Mouse 2023
    10. Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation Cell stem cell · 2012 · 321 citations
    All research results →

    Community 4 of 134

    1. 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2 Reddit · 29 Jul 2024
    2. bro where tf is GT20029, Q1 2024 is over already Reddit · 12 Apr 2024
    3. True hair loss Vs shedding cycle Reddit · 8 Feb 2026
    4. Anyone heard of HairStemCell Transplant? They claim not needing to pull the entire hair cell, allowing reuse of same donor area. Reddit · 10 May 2018
    All community results →

    Learn 5 of 20

    1. Procyanidin Plant polyphenol found in apples and grape seeds
    2. Rapamycin Immune-suppressing drug, also called sirolimus
    3. Alopecia Areata autoimmune disorder causing patchy hair loss
    4. Neem Oil Oil from the neem tree, used in traditional remedies
    5. Stem Cell Factor
    All learn results →