Search

for
Search:

Did you mean Caspase-1?

GlossaryCaspase-1

enzyme activating inflammatory cytokines and inducing cell death

Caspase-1, also known as Interleukin-1 converting enzyme (ICE), is an enzyme that plays a crucial role in the inflammatory response by activating pro-inflammatory cytokines like interleukin-1β (IL-1β) and interleukin-18 (IL-18). It is also involved in a form of programmed cell death called pyroptosis, which helps the body fight infections by eliminating infected cells.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 1000+ results

research Expression of Caspase-14 and Keratin-19 in the Human Epidermis and Appendages During Fetal Skin Development

19 citations , February 2013 in “Archives of Dermatological Research”

research RNase L Acts as a Regeneration Suppressor

April 2023 in “Journal of Investigative Dermatology”

RNase L suppresses regeneration in mammals.

research Cell Death by Cornification

375 citations , June 2013 in “Biochimica et biophysica acta. Molecular cell research”

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

research Inflammation in Androgenetic Alopecia and Hair Loss: Linking Neurosciences, Endocrinology, and Dermatology

1 citations , May 2012 in “Hair transplant forum international”

Hair loss in men may be caused by inflammation triggered by hormones, and treatments reducing inflammation could potentially promote hair growth.

Immunomodulatory Effects of Platelet-Rich Plasma on Neuroinflammation: Insights from BV2 Glial Cells Stimulated with Heat-Killed Escherichia Coli

research Immunomodulatory Effects of Platelet-Rich Plasma on Neuroinflammation: Insights from BV2 Glial Cells Stimulated with Heat-Killed Escherichia Coli

November 2025

PRP may help reduce brain inflammation and protect brain cells.

View more "caspase-14" in research →

Community Join

2 / 2 results

community Hair loss causes are still a myth.

in Chat 17 upvotes 4 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.

community Don't use PP405 from everychem. it is likely fake.

in Research/Science 65 upvotes 8 months ago

PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.