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GlossaryCaspase-7 (CASP7)

enzyme involved in programmed cell death (apoptosis)

Caspase-7, also known as CASP7, is an enzyme that plays a crucial role in the process of apoptosis, which is the programmed cell death essential for maintaining healthy tissue and organ function. It is part of a family of proteases that, when activated, can break down cellular components, leading to the orderly and efficient removal of damaged or unnecessary cells. This process is vital for development, immune system function, and preventing diseases such as cancer.

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research Evaluation of the Expression of Genes Associated with Inflammation and Apoptosis in Androgenetic Alopecia by Targeted RNA-Seq

8 citations, December 2017 in “Skin appendage disorders”

WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.

research The Inflammatory Aspect of Male and Female Pattern Hair Loss

November 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Inflammation plays a key role in male and female pattern hair loss, and focusing on this could help develop better treatments.

research Non-Apoptotic Role for Caspase-7 in Hair Follicles and Surrounding Tissue

6 citations, August 2015 in “Journal of Molecular Histology”

Caspase-7 has functions in skin and hair that are not related to cell death.

research The Inflammatory Aspect of Male and Female Pattern Hair Loss

9 citations, November 2020 in “Journal of Inflammation Research”

Inflammation affects hair loss; anti-inflammatory treatments may help.

research Understanding Autoimmunity of Vitiligo and Alopecia Areata

74 citations, May 2016 in “Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics”

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

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community 1 year of finasteride and 5 months of oral minoxidil, nizoral and microneedling

in Progress Pictures 54 upvotes 1 year ago

User shared 1-year finasteride and 5-month oral minoxidil, nizoral, and microneedling progress. Reply suggests full results may appear after 1-2 years, and results look promising.

community Hair loss causes are still a myth.

in Chat 16 upvotes 3 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.