29 citations
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April 2019 in “Acta neuropathologica communications” This study found that β-sitosterol, a brain-penetrable phytosterol, reduced melanoma cell growth and brain metastasis formation by interfering with mitochondrial respiration, suggesting its potential as an adjuvant therapy to BRAF inhibitors for patients with melanoma brain metastases.
16 citations
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December 2021 in “Journal of Integrative Neuroscience” This study found that upregulating miR-325-3p in glioma suppresses tumor cell proliferation, migration, and invasion by inhibiting FOXM1, suggesting its potential as a treatment target for brain cancer.
19 citations
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November 2015 in “Radiation Oncology” This study found that hippocampus sparing whole brain radiation therapy (HS-WBRT) using multi-field intensity modulated radiation therapy prevents alopecia without compromising cognitive function compared to traditional whole brain radiation therapy.
1 citations
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July 2020 in “International journal of radiology & radiation therapy” This study found that VMAT hair-sparing WBRT partially preserved scalp hair at four weeks post-treatment without compromising symptomatic disease control in the short term, but reduced hair loss did not improve quality of life.
6 citations
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January 2015 in “Evidence-based Complementary and Alternative Medicine” This study found that saw palmetto extract inhibits glioma cell proliferation and angiogenesis via the STAT3 pathway, suggesting its potential use as a complementary therapy for cancers with activated STAT3 signaling.