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    GlossaryBiological Pathways

    interconnected biochemical reactions within cells for specific functions

    Biological pathways, also known as biochemical pathways, are series of interconnected biochemical reactions that occur within a cell or organism to carry out specific functions, such as energy production, cell signaling, or metabolism. These pathways involve enzymes and other molecules that work together to convert substrates into products, ultimately supporting the organism's growth, development, and homeostasis.

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      community Story time! The Great Unbalding (PP405)

      in Research/Science  225 upvotes 6 days ago
      PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 11 months ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Topical finasteride now the safest possible path?

      in Finasteride/Dutasteride  84 upvotes 1 year ago
      Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

      community Massive study on finasteride side effects released

      in Finasteride/Dutasteride  83 upvotes 2 years ago
      The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.