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30 / 1000+ resultsresearch Exploring the Anti-Seborrheic Dermatitis Potential of Prunus armeniaca L. Seed Oil: A Stereological, Biochemical and Molecular Study on MMP-9, MMP-2, CCR-5 and VEGF Pathways in a Rat Model
This animal study found that Prunus armeniaca L. seed oil improved inflammatory markers, oxidative stress levels, and skin structure in DNFB-induced seborrheic dermatitis in rats, suggesting its potential role in managing this condition.
research Alopecia - the search for novel agents continues
This review discusses nearly 70 patent applications for the treatment of androgenetic alopecia and other hair conditions, highlighting the mechanisms of action explored but reports no clinical results.
research Dietary Aspects for Selenium and/or Selenium Compounds
This review discusses the dual role of selenium in human health, highlighting both the dangers of deficiency and potential toxicity from over-supplementation, without presenting new clinical results.
research Hair structure anatomy and comparative anatomy1 1Dedicated to the memory of the late Dr. R. E. Rivett whose untimely death prevented his role in co-authorship.
This paper reviews the complex anatomy and development of human hair and emphasizes the need to understand these processes for interpreting drug incorporation into hair, with no new clinical results reported.
research Effect of Laser and Light-Based Systems on Hair Follicle Biology
This review discusses the mechanisms by which laser treatment affects hair structures and growth, highlighting its potential for permanent hair reduction and associated skin damage, but reports no new experimental results.
research Biology of Human Hair: Know Your Hair to Control It
This review covers various aspects of hair biology, pigmentation, and development, focusing on genetic and biochemical modulation of hair follicle components but reports no new findings.
research BIOCHEMICAL FACTORS INFLUENCING FAMILIAL HIRSUTISM IN THE SOUTHERN REGION OF KPK
This study found that women with familial hirsutism in southern Khyber Pakhtunkhwa, Pakistan, exhibited elevated androgen levels and insulin resistance compared to controls, suggesting a significant hereditary and hormonal basis for the condition.
research Signaling pathways in the mechanisms of drug action
This study reviewed literature on signaling pathways and concluded that these pathways are crucial pharmacological targets, influencing the mechanisms of drugs used in neurological, cardiovascular, and oncological treatments to correct signal transmission disturbances.
research [Trichothiodystrophy: a morphological and biochemical study].
This study reports that despite normal cystine incorporation into hair follicles, trichothiodystrophy patients have decreased cystine levels in hair shafts, contradicting the hypothesis of defective transport in hair follicles.
research Role of cholesterol sulfate in epidermal structure and function: Lessons from X-linked ichthyosis
This paper discusses X-linked ichthyosis and its genetic causes, focusing on biochemical pathways and their role in epidermal differentiation and barrier function, but it presents no new clinical findings.
research From hair colour to diagnosis
This review discusses recent advances in the understanding of follicular melanogenesis and its pathological changes, particularly how these changes are associated with specific disease phenotypes, but it reports no new results.
research POLYCOMB REPRESSIVE COMPLEX 1 IS REQUIRED TO MAINTAIN STEM CELL IDENTITY AND TO PRESERVE ADULT TISSUE HOMEOSTASIS.
This study found that Polycomb Repressive Complex 1 is crucial for maintaining stem cell identity across different lineages, but its loss results in varied transcriptional outcomes depending on the tissue context.
research Hair Follicle Pigmentation
This article reviews follicular melanogenesis, detailing how melanin synthesis and its regulation in hair follicles depend on a complex interplay of cellular and molecular mechanisms, but reports no new clinical findings.
research Formation of the cornified envelope
This review discusses the formation and structure of the cornified cell envelope in the epidermis, highlighting biochemical pathways and genetic factors, but presents no new experimental results.
research Effects of Wet Cupping on Blood Components Specially Skin-Related Parameters of Healthy Cases: A Case Control Metabonomic Study
This study found that wet cupping blood differs significantly from venous blood in metabolite profiles, implying distinct biochemical pathways may be involved.
research Low Anabolic Profile in Assessing a Patients Overall Hair Loss
This investigation found that certain supplements, particularly whey protein isolate, growth hormones, and anabolic steroids, can negatively impact hair loss by affecting biochemical pathways.
research PEGylated thymosin β4 is a thiol‐site‐specific prodrug treating myocardial infarction in vivo
This study reported that a modified version of Thymosin beta 4, called PEG-rTβ4, demonstrated potential as a treatment for acute myocardial infarction by improving cardiac function and reducing cell death via specific biochemical pathways, suggesting its promise in drug development efforts.
research A Platform for Determining Medicinal Plants with Targeted 17β-Hydroxysteroid Dehydrogenase Modulation for Possible Hair Loss Prevention
In this study, researchers developed a novel platform for discovering potential hair loss inhibitors by investigating the testosterone/dihydrotestosterone biosynthetic pathway and its regulation through biochemical mechanisms involving 17β-HSD and 3β-HSD, combined with medicinal plant extracts.
research Epigenetic Effects of Finasteride on Human Leydig Cells
This study identified specific genes and pathways in human Leydig cells that may contribute to Post-finasteride Syndrome, potentially informing future treatments to reverse persistent side effects.
research Biotinidase deficiency: a survey of 10 cases.
This study found that while biotin treatment improves clinical and biochemical symptoms in patients with biotinidase deficiency, some experience lasting neurological damage, and it is uncertain if early treatment can prevent this.
research High spatial resolution study of human skin using synchrotron infrared microscopy: application to the penetration of external agents
In this study, synchrotron-powered infrared microscopy revealed that hair follicles are a favored penetration pathway for cyanophenol and ethylhexyl methoxycinnamate in human skin, without altering protein secondary structure.
research A Comprehensive Review of Mammalian Pigmentation: Paving the Way for Innovative Hair Colour-Changing Cosmetics
This review highlights the possibility of safely altering hair color through innovative cosmetics by targeting key biological processes in hair follicles, using insights from mammalian pigmentation studies and drug-induced hair color changes as potential pathways.
research The Carnivore Follicular Integrity Framework (CFIF): An Evolutionary-Mechanistic Model of Hair Follicle Stability, Regenerative Peptide Biology (GHK-Cu), and Anti-Glycation Microvascular Protection
This theoretical research project proposes the Carnivore Follicular Integrity Framework, suggesting that animal-based diets may support hair follicle stability through various evolutionary and mechanistic pathways.
research Unravelling the molecular basis for symbiotic signal transduction in legumes
This article reviews the molecular events in legume-rhizobia symbiosis, focusing on gene regulation, symbiotic pathways, and infection processes, but does not present new experimental findings.
research Low Anabolic Profile in Assessing a Patient’s Overall Hair Loss
This paper reports that certain supplements, particularly whey protein isolate, growth hormones, and anabolic precursors, have a significant negative effect on hair loss.
research METABOLISM AND ACTION OF ANDROGEN IN THE SKIN
This article reviews the metabolism and action of androgen in the skin but reports no new experimental results; the author calls for further research.
research Hair Graying: Mechanisms, Prevention, and Innovative Treatment Strategies – literature review
This review explores the complex biological process of hair graying, highlighting oxidative stress, genetic factors, and interventions like antioxidants and genetic therapy as key aspects affecting the preservation of hair pigmentation.
research How Does Altered Metabolism Lead to Seizure Control? Partially Filling the Knowledge Gap
This study found that when metabolism changes and extracellular glucose decreases, hippocampal CA3 neurons release ATP, which is converted to adenosine and reduces neuron excitability, enhancing the seizure threshold.
research Advancing human adipose-derived mesenchymal stem cell-derived exosomes for androgenetic alopecia: Appraisal and methodological recommendations
This study identified 232 stable proteins in exosomes from human adipose-derived mesenchymal stem cells and suggested a signaling axis that might support future androgenetic alopecia treatments.