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Did you mean Androgenic Effects?

Glossary Androgenic Effects

influence of male sex hormones on physical traits

Androgenic effects refer to the influence of androgens, which are male sex hormones like testosterone, on the body. These effects include the development of male characteristics such as facial hair, deepening of the voice, and increased muscle mass. In both men and women, androgens can also impact hair growth patterns, potentially leading to conditions like androgenic alopecia (pattern baldness).

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Research

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research Androgenic Effects on Ventricular Repolarization

64 citations , August 2019 in “Circulation”

This study found that men receiving enzalutamide and other androgen-deprivation therapies may be at increased risk for QT prolongation and torsades de pointes.

research Androgenic effects of oral contraceptives: Implications for patient compliance

22 citations , January 1995 in “The American Journal of Medicine”

This article reviews the negative effects of androgenic disorders and highlights that newer oral contraceptives with less androgenic progestins may reduce these effects and improve compliance, but it reports no new results.

research Androgenic and anti-androgenic effects of progesterone derivatives with different halogens as substituents at the C-6 position

19 citations , June 1999 in “Steroids”

This study found that compound 10 inhibited testosterone conversion to DHT in hamster flank organs and seminal vesicles, whereas compound 11's inhibitory effect varied with dose, linked to halogen electronegativity differences.

research Exclusive androgenic effect of dehydroepiandrosterone in sebaceous glands of rat skin

11 citations , August 2000 in “Journal of Endocrinology”

In this study, treatment with DHEA induced mild to moderate hyperplasia of sebaceous glands in ovariectomized rats, which was prevented by the antiandrogen Flutamide but not by the antiestrogen EM-800.

research Androgenic effect of testosterone and some of its metabolites in relation to their biotransformation in the skin.

11 citations , November 1982 in “British journal of dermatology/British journal of dermatology, Supplement”

In this study, testosterone and certain metabolites were highly effective in promoting sebaceous structure growth in the female hamster flank organ, while others had limited or no effect.

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Community Join

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community Bicalutamide effect on androgens?

5 upvotes 5 years ago

Bicalutamide blocks androgen receptors, preventing testosterone and DHT from binding, which can help with hair loss but may cause feminization. It is not recommended for those who do not want feminization effects.

community How effective is topical spironolactone for androgenic alopecia?

in Female 1 upvotes 1 year ago

Topical spironolactone is discussed as a potential treatment for androgenic alopecia, with the user seeking feedback on its effectiveness. Minoxidil, finasteride, and other treatments like microneedling and keto shampoo are mentioned as alternatives.

community Does the effect of spironolactone on androgenetic alopecia really weaken over time?

4 upvotes 1 year ago

Spironolactone can remain effective for a long time in treating androgenetic alopecia, but it may not completely stop hair loss. Hair loss treatments like spironolactone, finasteride, and dutasteride slow down hair loss rather than cure it, and their effectiveness can vary based on individual response and the aggressiveness of the condition.

community Soy consumption may offer protective effects against androgenic alopecia

4 upvotes 9 years ago

Soy consumption may help prevent androgenic alopecia, but it can decrease sexual drive in some men. There is a connection between soy and androgenic alopecia, suggesting a potential protective effect.

community If RU58841 is such an effective anti androgen

in Research/Science 46 upvotes 2 years ago

RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

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Learn

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learn Verteporfin

Is Verteporfin effective for both androgenic alopecia and alopecia areata? Verteporfin has never been tested in people with pattern hair loss or alopecia areata. It is an eye drug with only mouse wound data behind the hair interest.

learn Cetirizine

Is topical cetirizine effective for androgenetic alopecia in women? Topical cetirizine is not an approved product and its use for female-pattern hair loss is off-label. The evidence is one small pilot study in mixed-sex patients and one randomized trial in 66 women where cetirizine was added to minoxidil; it is unproven on its own.

learn GT20029

Is GT20029 safe and effective for both men and women with androgenic alopecia? Not known yet. GT20029 is an experimental drug tested only in men: in one 12-week trial two of four regimens beat placebo with similar side-effect rates, and long-term safety and effects in women or pregnancy are unstudied.

learn Procyanidin

Are Procyanidin based hair tonics or shampoos effective against androgenic alopecia? Three small trials of topical procyanidin in 29 to 43 men, all run by the company that developed it, reported modest hair-count gains after four to six months. No independent trial has confirmed them, and procyanidin is not an approved treatment for pattern hair loss.

learn Hair Transplant

Can women get hair transplants? Some women are candidates for a hair transplant, but diffuse thinning and a thin donor area limit who is suitable. Clinics say a careful assessment of the cause comes first.