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    Did you mean Selective Androgen Receptor Modulators?
    Glossary Selective Androgen Receptor Modulators

    compounds that selectively target androgen receptors to promote muscle growth

    Selective Androgen Receptor Modulators (SARMs) are a class of compounds that bind to androgen receptors in the body, similar to anabolic steroids, but with more targeted effects. They are designed to selectively stimulate muscle and bone growth without significantly affecting other tissues, potentially offering therapeutic benefits for conditions like muscle wasting and osteoporosis with fewer side effects compared to traditional steroids.

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    Research 10 of 1000+

    1. Design, Synthesis, and Biological Characterization of Metabolically Stable Selective Androgen Receptor Modulators Journal of medicinal chemistry · 2004 · 129 citations
    2. Androgen receptor modulators: a review of recent patents and reports (2012-2018) Expert Opinion on Therapeutic Patents · 2019 · 23 citations
    3. QSAR Analysis of a Series of Hydantoin‐based Androgen Receptor Modulators and Corresponding Binding Affinities Molecular Informatics · 2019
    4. A phase IIA randomized, placebo-controlled clinical trial to study the efficacy and safety of the selective androgen receptor modulator (SARM), MK-0773 in female participants with sarcopenia Journal of Nutrition Health & Aging · 2013 · 211 citations
    5. Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands 2009 · 36 citations
    6. Improving selective androgen receptor modulator discovery and preclinical evaluation Expert Opinion on Drug Discovery · 2009 · 11 citations
    7. The Mechanisms of Anabolic Steroids, Selective Androgen Receptor Modulators and Myostatin Inhibitors 대한스포츠의학회지 · 2022 · 2 citations
    8. Abstract P5-09-21: Selective androgen receptor modulators (SARMs): Enobosarm as targeted therapy for the treatment of androgen receptor-positive breast cancer Cancer research · 2013 · 2 citations
    9. Crystallization and preliminary X-ray analysis of the human androgen receptor ligand-binding domain with a coactivator-like peptide and selective androgen receptor modulators Acta crystallographica · 2008 · 1 citations
    10. Selective Androgen Receptor Modulator, YK11, Up-Regulates Osteoblastic Proliferation and Differentiation in MC3T3-E1 Cells Biological and Pharmaceutical Bulletin · 2018 · 23 citations
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    Community 10 of 345

    1. Help! Gyne after 20 years of taking Dut Reddit · 11 Aug 2024
    2. Could a reversed SARM designed for the scalp serve as a replacement for oral Dut and Fin? Reddit · 2 Dec 2024
    3. How can ketoconazole shampoo block androgen receptor if it's just washed off? Reddit · 11 Nov 2025
    4. Fluridil degrades the androgen receptor. Reddit · 11 Jun 2025
    5. Having androgen receptor density and sensitivity at wrong f*ing place Reddit · 17 Oct 2024
    6. Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight? Reddit · 22 May 2024
    7. Theaflavin (Black Tea Extract) reduce DHT, androgen receptor activity and estrogen Reddit · 20 Jul 2023
    8. Has anyone powered through the creatine shedding (via increased androgen receptor sensitivity) and stabilized? Reddit · 21 Aug 2025
    9. Dutasteride: More Than a DHT Reducer – A Potential Androgen Receptor Inhibitor? Reddit · 20 Dec 2024
    10. If we lose hair because of our sensitivity to DHT, then why are we trying to reduce DHT when our sensitive androgen receptors are the culprit? Reddit · 6 Apr 2022
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    Learn 8 of 12

    1. Clascoterone Topical androgen-receptor blocker, approved as an acne cream
    2. GT20029 Experimental topical drug designed to break down androgen receptors
    3. Cyproterone a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
    4. Pyrilutamide Experimental topical anti-androgen, also known as KX-826
    5. Bicalutamide Nonsteroidal anti-androgen, originally a prostate cancer drug
    6. RU58841 Experimental topical anti-androgen sold as a research chemical
    7. Spironolactone Blood-pressure and diuretic drug with anti-androgen effects
    8. Fluridil Topical anti-androgen sold as a cosmetic lotion
    All learn results →