research Aging, alopecia, and stem cells
The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.
Search
forResearch
5 / 1000+ results research Gas-propelled anti-hair follicle aging microneedle patch for the treatment of androgenetic alopecia
This study developed a gas-propelled microneedle patch with puerarin/quercetin nanoparticles, which demonstrated improved hair-regenerating effects in an androgenetic alopecia mouse model by increasing drug delivery, alleviating oxidative stress, promoting angiogenesis, and rejuvenating senescent cells.
research Cellular Senescence: Ageing and Androgenetic Alopecia
This review summarizes biological links between aging and androgenetic alopecia, particularly focusing on cellular senescence, and discusses potential therapeutic strategies, but reports no new clinical results.
research Anti-aging effects of black raspberry extract on cataract, alopecia, skin whitening, and weight loss
This study found that berry extracts, especially black raspberry extract, may have anti-aging effects due to their high antioxidant activities.
research P02 Accelerated ageing of hair follicles in androgenetic alopecia
In this study, researchers found that frontal hair follicles in individuals with androgenetic alopecia show a higher biological age compared to occipital follicles, possibly due to decreased expression of the transcriptional repressor TRPS1 in frontal dermal papillae, which may influence follicle miniaturization.
Community Join
5 / 451 resultscommunity Perifollicular Fibrosis and its role in androgenetic alopecia. Is Aminexil/Kopexil a must for anyone with AGA?
Aminexil/Kopexil may help reduce hair loss by addressing perifollicular fibrosis in androgenetic alopecia, but it lacks the extensive clinical backing of finasteride and minoxidil. Some users find it effective, but availability and cost are issues, especially in the US where it's not FDA-approved.
community Bruteforcing alopecia or the new advent of science progress
Combining therapies like scyllo-inositol, alpha-ketoglutarate, and autophagy-inducing supplements may enhance hair growth and prevent hair loss. Reporting individual results can accelerate progress in hair loss treatments.
community The Real Cause Of Androgenetic Alopecia
Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.
community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.
A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.
community Does finasteride/dutasteride reverse aging?
Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.
Learn
9 / 801 results- Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.
- Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.
- Got small bald patches they say are from stress? PP405 sprays could help bring them back to life. PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.
- What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.
learn Rapamycin
mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth
learn Overview
learn Dexpanthenol
precursor of vitamin B5 with hair stimulating effects
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Melatonin
hormone commonly taken for sleep aid has some topical benefits for hair
learn Centella
learn GHK-Cu
learn PP405
learn TDM-105795
Clinics
6 / 41 results- 46
SMPHair Loss TreatmentsThe Alopecia Doctor Hair and Scalp SpaHouston, TX · US - 15Hair SystemsGot Alopecia? Call Keisha!Atlanta, GA · US
- 15
Hair SystemsWhat Alopecia? Hair Replacement StudioLynchburg, VA · US - 15
Hair Loss Treatmentsomiosam - alopecia clinicAnaval, Gujarat · IN - 68
Hair Loss TreatmentsTrichologyAlopecia & Beyond Hair Clinic and Wellness SpaVaughan, ON · CA - 25
Hair SystemsTrichologyAlopecia DisruptedIndianapolis, IN · US
Experts
— no results