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research Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride

45 citations , August 2010 in “Hormone Molecular Biology and Clinical Investigation”

This study found that SRD5a-3 is a highly efficient enzyme for converting hormones into androgens, with dutasteride being a much more potent inhibitor of SRD5a-3 than SRD5a-2.

research 3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid (TCQA)

2 citations , June 2022 in “Cells”

The study found that growing dermal papilla cells in 3D spheroids enhances their activity with hair growth-promoting agents, such as minoxidil and TCQA, compared to traditional 2D cultures.

research Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2

8 citations , June 2017 in “Steroids”

This study evaluated novel steroid compounds for their ability to inhibit 5α-reductase, showing that compound 16a significantly reduced rat prostate weight more than epristeride and exhibited excellent in vitro inhibitory potency, indicating its potential as a lead candidate for further benign prostatic hyperplasia drug research.

research Biological Activities of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside in Antiaging and Antiaging-Related Disease Treatments

43 citations , January 2016 in “Oxidative medicine and cellular longevity”

This review discusses the biological effects and mechanisms of THSG in antiaging and related disease treatments but reports no new experimental findings.

research β-catenin-mediated hair growth induction effect of 3,4,5-tri-O-caffeoylquinic acid

42 citations , June 2019 in “Aging”

This study found that treatment with the polyphenolic compound TCQA activated β-catenin, promoting hair regrowth and the initiation of the anagen phase in mice and human dermal papilla cells.

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community 3.5 months on 5% min. Will I keep improving? (36 M)

in Is this regrowth? 11 upvotes 2 years ago

A 36-year-old has been using 5% Minoxidil for 3.5 months and is considering adding microneedling and PRP. Another user suggests adding finasteride and microneedling for better results.

community 3.5 Month Diffuse Thinning Progress ( Same lighting attempt)

25 upvotes 1 month ago

The user shared their 3.5-month progress on treating diffuse thinning using 1mg finasteride daily, 5% minoxidil spray twice daily, microneedling every other week, and keto shampoo for dandruff. They reported positive results with no side effects and are considering a hair transplant in a year.

community 3.5 month dutasteride(1mg)+ vitamin D+ minoxidil %5 progress (24 years old).

in Progress Pictures 24 upvotes 1 year ago

A 24-year-old is experiencing hair shedding and regrowth while using dutasteride (1mg), vitamin D, and minoxidil (5%). Others share similar experiences with hair loss treatments like minoxidil and finasteride.

community 3.5-4 month progress is this hyper response?

in Progress Pictures 29 upvotes 2 years ago

A user shared their 3.5-4 month progress using Topical Minoxidil, Oral Finasteride, Keto 1%, and Dermastamp, reporting positive results despite some shedding and flaking. Replies praised the progress and inquired about the treatment routine and temple condition.

community my 3.5 months progress on finasteride 1 mg

in Progress Pictures 276 upvotes 4 months ago

The user experienced significant hair regrowth after 3.5 months of using finasteride 1 mg daily, despite stopping minoxidil after three weeks. They were surprised by the results and noted some weight gain but no significant side effects.

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Learn

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learn Hair Transplant

What happens after a hair transplant? Expect mild swelling and redness, with new hair growth starting in 3 to 6 months.
How much do hair grafts cost in India? Hair grafts in India typically cost between INR 45,000 and INR 3,00,000.
How many sessions will I need for a hair transplant? Providers give different answers, and the number is decided at consultation: some clinics quote courses of 3 to 6 sessions, but that pattern belongs to non-surgical treatments rather than to surgery. Ask your surgeon how many procedures your own case would need and how far apart they would be.

learn Scalp Micropigmentation

How long does Scalp Micropigmentation last, and does it need touch-ups over time? Scalp micropigmentation lasts 2 to 8 years and requires touch-ups every 1 to 5 years.
What should I avoid after scalp micropigmentation? Avoid sun exposure, swimming, sweating, and hair products after scalp micropigmentation.

learn Dutasteride

Heavy duty finasteride that comes with higher risks

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Overview

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