Immunomodulatory Potential and Biocompatibility of Chitosan-Hydroxyapatite Biocomposites for Tissue Engineering

June 2025 in “ Journal of Composites Science ”

Davide Frumento, Ştefan Ţălu

Studysummary This study investigated chitosan–hydroxyapatite biocomposites, finding them to enhance anti-inflammatory cytokine expression, support cellular activities, and reduce pro-inflammatory cytokines in a dermatitis model, while highlighting gaps in understanding their immune modulation and issues with reproducibility for clinical use.

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