Therapeutic Efficacy of Autologous Platelet-Rich Plasma and Polydeoxyribonucleotide on Female Pattern Hair Loss

December 2014 in “ Wound Repair and Regeneration ”

Si Hyeock Lee, Zhenlong Zheng, Jin U. Kang, Young Ho Kim, Sang Cheul Oh, Sung Bin Cho

platelet-rich plasma polydeoxyribonucleotide female pattern hair loss WNT PDGF FGF immature adipocytes alopecia lesions CD34+ cells leukocyte-rich PRP PRP PDRN FPHL

TLDR PRP injections may improve hair thickness and density in female hair loss patients.

This document discusses the therapeutic efficacy of autologous platelet-rich plasma (PRP) and polydeoxyribonucleotide (PDRN) on female pattern hair loss (FPHL). The study found that PRP injections induced the expression of WNT, PDGF, and FGF in rabbit skin, which may improve hair thickness and density in FPHL patients. The study suggests that PRP injections may be useful in treating FPHL by inducing PDGF expression in immature adipocytes of alopecia lesions. However, further studies are needed to confirm the clinical efficacy of autologous CD34+ cell-containing, leukocyte-rich PRP treatment in patients with pattern hair loss.

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