Tertiary Lymphoid Organs at the Center Stage of Skin's Humoral Immunity

    September 2025 in “ Immunological Reviews ”
    Inta Gribonika
    Studysummary This review describes how the skin can form its own immune response through dermal tertiary lymphoid organs, which function independently of traditional lymph nodes, potentially offering new insights into skin health care and treatments.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 7

    1. Advances In Polymeric Nano-Delivery Systems Targeting Hair Follicles For The Treatment Of Acne Drug Delivery · 2024
    2. Hair Follicle-Targeted Delivery of Azelaic Acid Micro/Nanocrystals Promotes the Treatment of Acne Vulgaris International journal of nanomedicine · 2024
    3. Hair Follicle-Targeting Drug Delivery Strategies for the Management of Hair Follicle-Associated Disorders Asian Journal of Pharmaceutical Sciences · 2022
    4. Genomic and Anatomical Comparisons of Skin Support Independent Adaptation to Life in Water by Cetaceans and Hippos Current Biology · 2021
    5. Functional Hair Follicle Regeneration: An Updated Review Signal Transduction and Targeted Therapy · 2021
    6. Stress-Induced Production of Chemokines by Hair Follicles Regulates the Trafficking of Dendritic Cells in Skin Nature Immunology · 2012
    7. The Human Hair Follicle: A Reservoir of CD40+ B7-Deficient Langerhans Cells That Repopulate Epidermis After UVB Exposure ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998