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      research Tertiary Lymphoid Organs at the Center Stage of Skin's Humoral Immunity

      September 2025 in “Immunological Reviews”
      This review describes how the skin can form its own immune response through dermal tertiary lymphoid organs, which function independently of traditional lymph nodes, potentially offering new insights into skin health care and treatments.
      Choreographing Immunity in the Skin Epithelial Barrier

      research Choreographing Immunity in the Skin Epithelial Barrier

      57 citations , March 2019 in “Immunity”
      This review discusses the roles of immune responses and cells in skin health and disease, emphasizing recent insights into their mechanisms and potential therapeutic applications, but presents no new experimental results.

      research Acne: Transient Arrest in the Homeostatic HostMicrobiota Dialog?

      22 citations , September 2019 in “Trends in Immunology”
      This paper proposes that acne vulgaris is a transient inflammatory response during adolescence due to changes in facial skin's microbiota and sebum environment rather than a stable skin condition.
      The Dynamics of the Skin’s Immune System

      research The Dynamics of the Skin’s Immune System

      306 citations , April 2019 in “International Journal of Molecular Sciences”
      This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.

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      community DHT Harms Scalp Microbiome: DHT Itch is REAL

       413 upvotes 1 year ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community What if DHT is not the vilan.

       13 upvotes 5 years ago
      Hair loss may be influenced more by inflammation, microbiome imbalances, and gut health than DHT. Treatments discussed include minoxidil, finasteride, RU58841, fecal microbiota transplants, and JAK inhibitors.

      community DHT Itch and Oily Scalp Explained (and how to fix it)

       90 upvotes 3 months ago
      Malassezia overgrowth can worsen oily scalp and inflammation, contributing to hair loss. Treatments include antifungal shampoos, C6/C8 MCT oil, low-dose isotretinoin, finasteride, and dutasteride.