Stem Cell Treatment in Hair Diseases

    Yeşim Akpınar Kara, Başak KANDİ
    TLDR Stem cell treatments show promise for treating hair loss.
    In recent years, regenerative treatments in dermatology gained importance, particularly for hair diseases, which were common complaints in dermatology clinics. Promising results from stem cell treatments for hair loss attracted attention. Mesenchymal stem cells, derived from various tissues, were used due to their multipotent nature and ability to differentiate into various cell types. These stem cells could be sourced from fetal cells (umbilical cord and amniotic sac) or adult cells (teeth, bone marrow, or adipose tissue). Adipose tissue-derived mesenchymal stem cells, obtained from white and brown fat tissue, were preferred for their cost-effectiveness and unlimited cell availability. These cells, also fibroblast and keratinocyte stem cells, played a crucial role in secreting growth factors and transforming into different cell types. Advances in the cellular and molecular biology of hair and skin led to the initiation of cell therapy in this field, with hair stem cells offering new hope for treating hair diseases. Hair follicles served as the primary source of multipotent stem cells in the skin, with the potential to renew the skin and restore hair follicles. The study aimed to discuss the use of stem cell therapies in treating hair diseases.
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