The Androgenic Alopecia Protective Effects of Forsythiaside-A and the Molecular Regulation in a Mouse Model

    March 2015 in “ Phytotherapy Research ”
    Heon-Sub Shin, Sang-Yong Park, Hyungeun Song … Tae-Hoo Yi
    Studysummary This study found that forsythiaside-A, a natural compound from Forsythia suspensa, was more effective than finasteride at preventing apoptosis of hair cells and delaying the catagen phase entry in an androgenic alopecia mouse model.
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    Research cited in this study 7

    1. Finasteride and Sexual Side Effects Indian Dermatology Online Journal · 2012
    2. Finasteride Induced Gynecomastia: Case Report and Review of the Literature International Journal of Trichology · 2009
    3. Value of Hormonal Levels in Patients with Male Androgenetic Alopecia Treated with Finasteride: Better Response in Patients Under 26 Years Old British Journal of Dermatology · 2008
    4. Evaluation of Androgens in the Scalp Hair and Plasma of Patients with Male-Pattern Baldness Before and After Finasteride Administration British Journal of Dermatology · 2006
    5. Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells Skin Pharmacology and Physiology · 2006
    6. Androgens and Alopecia Molecular and Cellular Endocrinology · 2002
    7. Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia British Journal of Dermatology · 2000

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    3. Lack of Effect of Topical Finasteride Suggests an Endocrine Role for Dihydrotestosterone Fertility and Sterility · 2000
    4. In Vivo Time-Dependent Inhibition of Human Steroid 5α-Reductase by Finasteride Journal of Pharmaceutical Sciences · 1996