Circulating and/or Cutaneous Irisin Resistance: A Novel Link Among Androgenetic Alopecia, Comorbid Metabolic Syndrome and Cardiovascular Risks

May 2023 in “ Journal of Cosmetic Dermatology ”

Noha Mohammed Dawoud, Marwa M. Dawoud, Sally M. El Hefnawy, Hayam A. Abdellatif, Naglaa H. Abdellatif, Sara S. Gaafar, Iman Seleit

androgenetic alopecia metabolic syndrome cardiovascular risks irisin energy metabolism BMI hypertension dyslipidemia serum irisin levels carotid intima-media thickness irisin resistance biomarker AGA MetS CIMT

Studysummary This study found that AGA patients had higher serum and epidermal irisin levels, which were associated with metabolic syndrome, dyslipidemia, and abnormal carotid intima media thickness, suggesting potential irisin resistance affecting cardiometabolic health.

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research Association of Androgenetic Alopecia with Metabolic Syndrome in Men: A Community-Based Survey

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This article discusses treatment approaches for female pattern hair loss and concludes that available medical treatments are effective in reversing or stabilizing the condition in most cases of mild-to-moderate severity.