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    Effects of Different Concentrations of Androgens on KAP24.1 Gene Expression in Hetian Sheep and Karakul Sheep

    June 2023 in “ Gene ”
    Shujuan Gong, Meiyan Liang, Ruijun Shi, Shuwei Li
    Studysummary In this study, researchers successfully cloned the KAP24.1 gene from sheep to analyze its expression in skin and hair follicles, finding that Mountain-type Hetian sheep showed the highest levels of expression and that androgen concentration significantly influenced KAP24.1 protein expression.
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    Research cited in this study 7

    1. The Complexity of the Ovine and Caprine Keratin-Associated Protein Genes International journal of molecular sciences · 2021
    2. De Novo Filament Formation by Human Hair Keratins K85 and K35 Follows a Filament Development Pattern Distinct from Cytokeratin Filament Networks FEBS open bio · 2021
    3. Characterization of an Ovine Keratin Associated Protein Gene, Producing a Protein Rich in Glycine and Tyrosine, Lacking in Cysteine Genes · 2019
    4. Wool Keratin-Associated Protein Genes in Sheep: A Review Genes · 2016
    5. An Updated Nomenclature for Keratin-Associated Proteins International Journal of Biological Sciences · 2012
    6. Characterization and Expression Analysis of KAP7.1 and KAP8.2 Genes in Liaoning New-Breeding Cashmere Goat Hair Follicles Molecular biology reports · 2010
    7. Characterization of Human KAP24.1, A Cuticular Hair Keratin-Associated Protein with Unusual Amino Acid Composition and Repeat Structure ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2007